| SP | Peralta, F.Peralta, Freddy >> | 29 | 2025 | R | 84 | 33 | 33 | 15 | 9 | 3.01 | .295 | 1.23 | 7.9 | 3.2 | 8.6 | 191.1 | 167 | 70 | 64 | 13 | 68 | 183 | 0 | 0 | 0 | 0 | 18 | 5 | 6 | 3.12 |
| SP | Nelson, J.Nelson, Jimmy >> | 28 | 2017 | R | 35 | 12 | 12 | 5 | 5 | 4.03 | .273 | 1.06 | 6.8 | 2.8 | 8.8 | 73.2 | 55 | 35 | 33 | 8 | 23 | 71 | 0 | 0 | 0 | 0 | 5 | 5 | 0 | 3.63 |
| SP | Gallardo, Y.Gallardo, Yovani >> | 25 | 2011 | R | 42 | 32 | 32 | 14 | 13 | 4.33 | .306 | 1.30 | 8.7 | 3.1 | 8.0 | 208.0 | 200 | 105 | 100 | 26 | 71 | 186 | 0 | 0 | 0 | 0 | 18 | 4 | 6 | 3.92 |
| SP | Greinke, Z.Greinke, Zack # >> | 28 | 2011 | R | 46 | 32 | 32 | 6 | 19 | 5.55 | .336 | 1.50 | 10.7 | 2.8 | 8.5 | 198.0 | 235 | 125 | 122 | 22 | 62 | 187 | 0 | 0 | 0 | 0 | 14 | 3 | 12 | 3.54 |
| SP | Marcum, S.Marcum, Shaun # >> | 30 | 2011 | R | 55 | 32 | 32 | 12 | 12 | 4.78 | .311 | 1.32 | 9.1 | 2.8 | 6.5 | 199.2 | 201 | 109 | 106 | 24 | 63 | 143 | 0 | 0 | 0 | 0 | 19 | 6 | 3 | 4.17 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 99 | 55 | 0 | 2 | 6 | 2.35 | .258 | 1.03 | 5.8 | 3.5 | 13.7 | 61.1 | 39 | 17 | 16 | 3 | 24 | 93 | 0 | 37 | 5 | 0 | 0 | 1 | 0 | 1.82 |
| SU | Jeffress, J.Jeffress, Jeremy >> | 30 | 2018 | R | 79 | 48 | 0 | 0 | 3 | 3.14 | .332 | 1.44 | 6.5 | 6.5 | 9.0 | 43.0 | 31 | 16 | 15 | 1 | 31 | 43 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Burnes, C.Burnes, Corbin >> | 23 | 2018 | R | 75 | 74 | 0 | 1 | 1 | 3.66 | .289 | 1.21 | 7.7 | 3.3 | 5.6 | 83.2 | 71 | 35 | 34 | 5 | 30 | 52 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 3.65 |
| RP | Fingers, R.Fingers, Rollie >> | 36 | 1982 | R | 64 | 43 | 0 | 5 | 1 | 2.76 | .279 | 1.14 | 7.7 | 2.6 | 7.7 | 49.0 | 42 | 15 | 15 | 6 | 14 | 42 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 3.80 |
| RP | Axford, J.Axford, John >> | 28 | 2011 | R | 56 | 22 | 0 | 2 | 2 | 3.20 | .298 | 1.27 | 9.5 | 2.4 | 10.9 | 19.2 | 20 | 7 | 7 | 2 | 5 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.74 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 64 | 21 | 0 | 1 | 0 | 6.55 | .365 | 1.68 | 11.0 | 4.1 | 10.6 | 22.0 | 27 | 16 | 16 | 6 | 10 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.68 |
| SP | Priester, Q.Priester, Quinn # >> | 24 | 2025 | R | 36 | 14 | 8 | 1 | 5 | 5.47 | .304 | 1.31 | 9.7 | 2.2 | 5.9 | 75.2 | 81 | 49 | 46 | 11 | 18 | 49 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.32 |