| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 15 | 15 | 6 | 6 | 3.83 | .300 | 1.29 | 9.2 | 2.4 | 9.0 | 89.1 | 91 | 40 | 38 | 13 | 24 | 89 | 1 | 0 | 0 | 1 | 6 | 0 | 3 | 3.71 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 15 | 15 | 3 | 9 | 6.92 | .362 | 1.69 | 11.8 | 3.5 | 6.7 | 78.0 | 102 | 64 | 60 | 16 | 30 | 58 | 2 | 0 | 0 | 0 | 5 | 1 | 0 | 5.37 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 15 | 15 | 5 | 7 | 4.66 | .319 | 1.38 | 9.1 | 3.4 | 4.8 | 92.2 | 93 | 48 | 48 | 7 | 35 | 49 | 2 | 0 | 0 | 1 | 7 | 2 | 1 | 4.13 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 15 | 15 | 7 | 7 | 4.37 | .317 | 1.37 | 8.6 | 3.8 | 5.0 | 107.0 | 102 | 54 | 52 | 5 | 45 | 60 | 3 | 0 | 0 | 0 | 8 | 2 | 1 | 3.80 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 48 | 0 | 3 | 1 | 3.15 | .265 | 1.07 | 8.4 | 1.2 | 7.2 | 60.0 | 56 | 21 | 21 | 7 | 8 | 48 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.37 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 34 | 0 | 0 | 3 | 4.58 | .287 | 1.21 | 8.3 | 2.7 | 11.9 | 37.1 | 34 | 20 | 19 | 6 | 11 | 49 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.35 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 29 | 0 | 3 | 1 | 3.08 | .265 | 1.08 | 8.1 | 1.7 | 7.8 | 38.0 | 34 | 13 | 13 | 7 | 7 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.21 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 21 | 0 | 1 | 2 | 4.99 | .316 | 1.29 | 8.5 | 3.2 | 7.2 | 39.2 | 37 | 23 | 22 | 7 | 14 | 31 | 0 | 4 | 0 | 0 | 0 | 4 | 3 | 5.13 |