| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 9 | 3 | 2.50 | .246 | 0.95 | 6.6 | 2.0 | 7.8 | 104.1 | 76 | 31 | 29 | 9 | 23 | 90 | 2 | 0 | 0 | 1 | 11 | 3 | 0 | 3.14 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 85 | 15 | 15 | 8 | 4 | 2.66 | .245 | 0.96 | 7.2 | 1.5 | 5.1 | 91.1 | 73 | 28 | 27 | 8 | 15 | 52 | 0 | 0 | 0 | 0 | 10 | 1 | 1 | 3.53 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 15 | 15 | 4 | 10 | 7.27 | .364 | 1.69 | 11.2 | 4.1 | 5.3 | 81.2 | 101 | 70 | 66 | 12 | 37 | 48 | 5 | 0 | 0 | 0 | 5 | 2 | 2 | 5.19 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 15 | 15 | 4 | 8 | 5.89 | .330 | 1.45 | 9.5 | 3.5 | 5.6 | 99.1 | 105 | 65 | 65 | 15 | 39 | 62 | 5 | 0 | 0 | 0 | 4 | 3 | 4 | 4.99 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 36 | 0 | 3 | 0 | 2.63 | .226 | 0.86 | 5.1 | 2.6 | 6.7 | 51.1 | 29 | 17 | 15 | 6 | 15 | 38 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 3.98 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 36 | 0 | 1 | 3 | 2.77 | .240 | 0.95 | 5.4 | 3.2 | 7.3 | 48.2 | 29 | 15 | 15 | 4 | 17 | 39 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 3.52 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 22 | 0 | 2 | 0 | 4.70 | .298 | 1.24 | 8.7 | 2.7 | 6.3 | 30.2 | 29 | 20 | 16 | 7 | 9 | 21 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.63 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 17 | 0 | 0 | 0 | 2.92 | .267 | 1.09 | 7.1 | 3.0 | 9.0 | 24.2 | 19 | 8 | 8 | 4 | 8 | 24 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.17 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 13 | 0 | 0 | 3 | 4.80 | .274 | 1.13 | 7.2 | 3.0 | 7.8 | 15.0 | 12 | 8 | 8 | 1 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.13 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 18 | 0 | 0 | 1 | 6.05 | .348 | 1.60 | 9.9 | 4.7 | 6.6 | 19.1 | 21 | 14 | 13 | 1 | 10 | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.79 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 5 | 0 | 0 | 1 | 3.97 | .277 | 1.15 | 4.9 | 5.7 | 2.5 | 11.1 | 6 | 5 | 5 | 3 | 7 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.91 |