| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 15 | 15 | 5 | 8 | 4.83 | .318 | 1.38 | 9.7 | 2.8 | 5.9 | 108.0 | 116 | 59 | 58 | 6 | 33 | 71 | 2 | 0 | 0 | 0 | 7 | 2 | 3 | 3.38 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 15 | 15 | 8 | 6 | 5.42 | .324 | 1.43 | 9.9 | 2.9 | 5.1 | 108.0 | 119 | 76 | 65 | 14 | 35 | 61 | 5 | 0 | 0 | 0 | 6 | 1 | 3 | 4.56 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 15 | 15 | 7 | 6 | 4.57 | .316 | 1.38 | 9.2 | 3.3 | 5.2 | 112.1 | 114 | 60 | 57 | 11 | 41 | 65 | 4 | 0 | 0 | 0 | 6 | 1 | 0 | 4.24 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 71 | 15 | 15 | 4 | 6 | 6.56 | .346 | 1.56 | 10.5 | 3.6 | 6.5 | 85.0 | 99 | 66 | 62 | 15 | 34 | 61 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 5.13 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 14 | 14 | 6 | 5 | 5.44 | .345 | 1.56 | 9.8 | 4.3 | 4.6 | 102.2 | 111 | 62 | 62 | 15 | 49 | 52 | 4 | 0 | 0 | 0 | 6 | 2 | 3 | 5.39 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 39 | 0 | 3 | 1 | 3.44 | .300 | 1.29 | 7.9 | 3.9 | 7.5 | 49.2 | 43 | 22 | 19 | 3 | 21 | 41 | 0 | 6 | 2 | 0 | 0 | 0 | 1 | 3.41 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 26 | 0 | 0 | 1 | 2.53 | .262 | 1.06 | 7.6 | 2.0 | 7.9 | 32.0 | 27 | 10 | 9 | 2 | 7 | 28 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 20 | 0 | 2 | 2 | 3.55 | .315 | 1.34 | 6.1 | 6.1 | 7.9 | 25.1 | 17 | 12 | 10 | 4 | 17 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.48 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 14 | 0 | 1 | 1 | 2.20 | .234 | 0.92 | 3.9 | 4.5 | 7.3 | 16.1 | 7 | 4 | 4 | 1 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.69 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 11 | 0 | 0 | 1 | 2.25 | .217 | 0.83 | 6.8 | 0.8 | 9.0 | 12.0 | 9 | 3 | 3 | 2 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.42 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 12 | 0 | 0 | 1 | 4.32 | .315 | 1.38 | 8.4 | 4.5 | 12.4 | 16.2 | 15 | 8 | 8 | 3 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.19 |