| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 45 | 31 | 31 | 7 | 14 | 4.46 | .329 | 1.45 | 9.5 | 3.6 | 5.4 | 200.0 | 210 | 107 | 99 | 20 | 79 | 119 | 1 | 0 | 0 | 1 | 17 | 5 | 5 | 4.37 |
| SP | Wakefield, T.Wakefield, Tim >> | 37 | 2003 | R | 32 | 30 | 29 | 2 | 15 | 6.02 | .365 | 1.71 | 10.4 | 5.0 | 5.6 | 163.0 | 189 | 113 | 109 | 20 | 90 | 102 | 0 | 0 | 0 | 0 | 12 | 2 | 8 | 5.04 |
| SP | Pennock, H.Pennock, Herb # >> | 26 | 1920 | L | 25 | 31 | 31 | 9 | 17 | 5.07 | .327 | 1.45 | 10.2 | 2.8 | 4.3 | 209.1 | 238 | 123 | 118 | 23 | 65 | 101 | 4 | 0 | 0 | 0 | 13 | 2 | 6 | 4.43 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 102 | 0 | 8 | 5 | 2.33 | .266 | 1.08 | 8.0 | 1.7 | 8.6 | 119.2 | 106 | 42 | 31 | 7 | 23 | 114 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 2.45 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 99 | 85 | 0 | 3 | 2 | 2.89 | .317 | 1.35 | 9.1 | 3.1 | 8.7 | 93.1 | 94 | 32 | 30 | 7 | 32 | 90 | 0 | 3 | 3 | 0 | 0 | 4 | 6 | 3.20 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 109 | 0 | 6 | 3 | 3.08 | .285 | 1.17 | 6.4 | 4.2 | 10.5 | 84.2 | 60 | 30 | 29 | 4 | 39 | 98 | 0 | 2 | 4 | 0 | 0 | 2 | 3 | 2.75 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 29 | 2009 | R | 30 | 68 | 0 | 3 | 5 | 3.42 | .269 | 1.09 | 5.9 | 4.0 | 9.0 | 84.1 | 55 | 38 | 32 | 5 | 37 | 84 | 0 | 5 | 5 | 0 | 0 | 1 | 0 | 3.13 |
| RP | Fornieles, M.Fornieles, Mike >> | 28 | 1960 | R | 22 | 59 | 0 | 6 | 2 | 3.99 | .338 | 1.50 | 8.8 | 4.7 | 3.6 | 88.0 | 86 | 45 | 39 | 7 | 46 | 35 | 0 | 6 | 1 | 0 | 0 | 3 | 3 | 4.91 |