| SP | Bumgarner, M.Bumgarner, Madison # >> | 26 | 2016 | L | 79 | 33 | 33 | 16 | 9 | 4.10 | .277 | 1.13 | 7.8 | 2.4 | 9.6 | 186.2 | 161 | 95 | 85 | 22 | 50 | 198 | 2 | 0 | 0 | 1 | 17 | 4 | 2 | 3.28 |
| SP | Perry, G.Perry, Gaylord >> | 30 | 1968 | R | 71 | 33 | 33 | 8 | 12 | 4.18 | .323 | 1.40 | 9.1 | 3.4 | 5.3 | 183.0 | 186 | 98 | 85 | 22 | 70 | 108 | 3 | 0 | 0 | 1 | 15 | 6 | 3 | 4.63 |
| SP | Mathewson, C.Mathewson, Christy # >> | 24 | 1904 | R | 65 | 33 | 33 | 8 | 14 | 4.66 | .312 | 1.35 | 9.0 | 3.2 | 4.5 | 173.2 | 173 | 98 | 90 | 16 | 61 | 87 | 5 | 0 | 0 | 2 | 13 | 2 | 1 | 4.29 |
| SP | Marquard, R.Marquard, Rube >> | 27 | 1913 | L | 64 | 30 | 30 | 8 | 15 | 4.21 | .312 | 1.36 | 9.8 | 2.4 | 4.7 | 173.1 | 189 | 91 | 81 | 16 | 46 | 91 | 3 | 0 | 0 | 0 | 17 | 1 | 1 | 3.97 |
| SP | Marichal, J.Marichal, Juan # >> | 31 | 1968 | R | 56 | 32 | 32 | 6 | 21 | 5.75 | .329 | 1.46 | 10.8 | 2.4 | 6.1 | 180.0 | 215 | 118 | 115 | 25 | 47 | 122 | 6 | 0 | 0 | 2 | 10 | 3 | 13 | 4.28 |
| RP | Walker, R.Walker, Ryan >> | 28 | 2024 | R | 77 | 72 | 0 | 2 | 2 | 3.08 | .257 | 1.00 | 6.6 | 2.5 | 8.7 | 84.2 | 62 | 35 | 29 | 5 | 23 | 81 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 2.77 |
| RP | Casilla, S.Casilla, Santiago >> | 34 | 2014 | R | 68 | 44 | 0 | 2 | 1 | 3.55 | .283 | 1.18 | 7.4 | 3.4 | 6.6 | 45.2 | 37 | 21 | 18 | 7 | 17 | 33 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.69 |
| RP | Garcia, J.Garcia, Jarlin >> | 28 | 2021 | L | 51 | 62 | 0 | 0 | 2 | 2.70 | .289 | 1.22 | 8.5 | 2.5 | 7.0 | 53.1 | 50 | 18 | 16 | 2 | 15 | 41 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.79 |
| CL | Romo, S.Romo, Sergio † >> | 28 | 2011 | R | 89 | 53 | 0 | 3 | 1 | 1.70 | .228 | 0.87 | 6.1 | 1.7 | 9.2 | 53.0 | 36 | 10 | 10 | 2 | 10 | 54 | 0 | 38 | 4 | 0 | 0 | 1 | 0 | 2.08 |