| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 21 | 28 | 28 | 14 | 9 | 4.84 | .325 | 1.43 | 8.7 | 4.2 | 7.9 | 176.2 | 171 | 99 | 95 | 16 | 82 | 154 | 0 | 0 | 0 | 0 | 13 | 2 | 8 | 3.86 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 6 | 28 | 28 | 10 | 11 | 5.34 | .326 | 1.42 | 8.9 | 4.0 | 9.3 | 156.2 | 154 | 93 | 93 | 23 | 69 | 162 | 1 | 0 | 0 | 0 | 12 | 4 | 8 | 4.24 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 5 | 28 | 28 | 6 | 9 | 5.73 | .347 | 1.58 | 9.1 | 5.2 | 8.9 | 130.1 | 131 | 84 | 83 | 22 | 75 | 129 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.99 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 3 | 27 | 27 | 5 | 13 | 5.62 | .334 | 1.48 | 9.6 | 3.7 | 6.7 | 133.0 | 142 | 88 | 83 | 29 | 55 | 99 | 0 | 0 | 0 | 0 | 9 | 3 | 5 | 5.65 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 60 | 64 | 0 | 2 | 4 | 4.37 | .323 | 1.42 | 7.9 | 5.0 | 10.6 | 80.1 | 70 | 40 | 39 | 12 | 44 | 94 | 0 | 7 | 5 | 0 | 0 | 1 | 4 | 4.29 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 57 | 64 | 0 | 3 | 6 | 3.05 | .259 | 1.05 | 7.2 | 2.4 | 9.7 | 88.2 | 70 | 30 | 30 | 9 | 23 | 95 | 0 | 6 | 5 | 0 | 0 | 0 | 1 | 2.95 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 49 | 58 | 0 | 7 | 4 | 3.64 | .261 | 1.05 | 7.2 | 2.3 | 8.6 | 71.2 | 57 | 32 | 29 | 8 | 18 | 68 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 48 | 42 | 0 | 1 | 2 | 5.62 | .349 | 1.61 | 9.4 | 5.3 | 7.9 | 41.2 | 43 | 27 | 26 | 7 | 24 | 36 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 5.22 |
| RP | DeJean, M.DeJean, Mike >> | 35 | 2005 | R | 20 | 41 | 0 | 3 | 0 | 1.47 | .250 | 0.98 | 6.4 | 2.4 | 7.2 | 49.0 | 35 | 8 | 8 | 2 | 13 | 39 | 0 | 4 | 1 | 0 | 0 | 1 | 5 | 2.80 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 29 | 2010 | L | 1 | 31 | 1 | 3 | 2 | 7.28 | .379 | 1.81 | 10.9 | 5.4 | 7.1 | 111.1 | 135 | 100 | 90 | 24 | 67 | 88 | 0 | 3 | 0 | 0 | 0 | 2 | 7 | 6.09 |