| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 25 | 32 | 32 | 14 | 11 | 5.25 | .348 | 1.57 | 9.3 | 4.8 | 7.1 | 193.2 | 200 | 115 | 113 | 21 | 104 | 152 | 2 | 0 | 0 | 0 | 14 | 6 | 7 | 4.55 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 14 | 32 | 32 | 7 | 15 | 5.62 | .336 | 1.51 | 9.5 | 4.2 | 8.5 | 177.2 | 187 | 116 | 111 | 34 | 82 | 168 | 0 | 0 | 0 | 0 | 15 | 1 | 4 | 5.01 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 12 | 32 | 32 | 5 | 11 | 6.05 | .365 | 1.71 | 10.1 | 5.4 | 8.0 | 148.2 | 166 | 104 | 100 | 27 | 88 | 132 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 5.41 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 10 | 32 | 32 | 7 | 7 | 5.84 | .334 | 1.49 | 9.8 | 3.7 | 5.9 | 152.2 | 166 | 99 | 99 | 34 | 62 | 100 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 5.86 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 57 | 85 | 0 | 12 | 3 | 4.34 | .314 | 1.35 | 6.5 | 5.7 | 8.5 | 110.0 | 79 | 56 | 53 | 5 | 70 | 104 | 0 | 2 | 4 | 0 | 0 | 2 | 6 | 3.66 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 54 | 82 | 0 | 7 | 3 | 3.55 | .259 | 1.05 | 7.3 | 2.1 | 7.9 | 109.0 | 88 | 44 | 43 | 16 | 26 | 96 | 0 | 7 | 5 | 0 | 0 | 0 | 4 | 3.86 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 43 | 70 | 0 | 3 | 5 | 6.08 | .336 | 1.51 | 10.6 | 2.9 | 9.5 | 77.0 | 91 | 60 | 52 | 13 | 25 | 81 | 0 | 9 | 5 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 48 | 61 | 0 | 7 | 5 | 3.56 | .279 | 1.13 | 7.0 | 3.2 | 10.0 | 73.1 | 57 | 29 | 29 | 6 | 26 | 81 | 0 | 3 | 2 | 0 | 0 | 2 | 5 | 3.00 |
| RP | DeJean, M.DeJean, Mike >> | 35 | 2005 | R | 19 | 41 | 0 | 0 | 1 | 4.53 | .357 | 1.62 | 11.6 | 3.2 | 7.2 | 45.2 | 58 | 23 | 23 | 5 | 16 | 36 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 4.04 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 29 | 2010 | L | 9 | 29 | 0 | 5 | 4 | 5.37 | .349 | 1.57 | 9.5 | 4.6 | 5.9 | 124.0 | 131 | 79 | 74 | 18 | 64 | 81 | 0 | 1 | 0 | 0 | 0 | 4 | 14 | 5.23 |