| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 27 | 32 | 32 | 9 | 17 | 4.92 | .334 | 1.49 | 9.0 | 4.4 | 7.5 | 205.0 | 206 | 114 | 112 | 22 | 100 | 171 | 0 | 0 | 0 | 0 | 15 | 3 | 10 | 4.23 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 16 | 32 | 32 | 13 | 9 | 4.80 | .338 | 1.51 | 9.3 | 4.3 | 8.2 | 185.2 | 192 | 101 | 99 | 21 | 88 | 169 | 0 | 0 | 0 | 0 | 13 | 4 | 0 | 4.14 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 15 | 32 | 32 | 9 | 12 | 5.89 | .371 | 1.75 | 9.7 | 6.1 | 7.6 | 149.2 | 161 | 98 | 98 | 19 | 101 | 126 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 5.06 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 13 | 33 | 32 | 10 | 10 | 6.64 | .361 | 1.69 | 11.7 | 3.5 | 6.3 | 145.0 | 188 | 107 | 107 | 22 | 57 | 102 | 0 | 0 | 0 | 0 | 5 | 1 | 4 | 4.77 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 61 | 87 | 0 | 6 | 3 | 2.46 | .266 | 1.09 | 4.5 | 5.2 | 10.6 | 117.0 | 59 | 32 | 32 | 5 | 68 | 138 | 0 | 5 | 3 | 0 | 0 | 0 | 4 | 2.94 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 57 | 85 | 0 | 3 | 5 | 4.39 | .298 | 1.26 | 9.1 | 2.3 | 10.1 | 110.2 | 111 | 55 | 54 | 11 | 28 | 123 | 0 | 7 | 6 | 0 | 0 | 2 | 1 | 2.88 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 49 | 72 | 0 | 4 | 5 | 3.87 | .280 | 1.14 | 8.3 | 2.0 | 7.8 | 88.1 | 81 | 38 | 38 | 18 | 20 | 76 | 0 | 9 | 3 | 0 | 0 | 2 | 0 | 4.68 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 51 | 51 | 0 | 2 | 3 | 7.36 | .381 | 1.85 | 9.8 | 7.1 | 9.4 | 47.2 | 51 | 39 | 39 | 9 | 37 | 49 | 0 | 6 | 3 | 0 | 0 | 0 | 3 | 5.77 |
| RP | DeJean, M.DeJean, Mike >> | 35 | 2005 | R | 20 | 39 | 0 | 1 | 1 | 7.88 | .341 | 1.53 | 9.7 | 4.1 | 6.5 | 40.0 | 43 | 36 | 35 | 9 | 18 | 29 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 5.90 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 29 | 2010 | L | 13 | 32 | 0 | 7 | 2 | 5.54 | .356 | 1.64 | 9.5 | 5.3 | 6.9 | 138.0 | 145 | 86 | 85 | 13 | 81 | 106 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 4.51 |