| SP | Kershaw, C.Kershaw, Clayton $$ >> | 28 | 2016 | L | 99 | 9 | 9 | 3 | 3 | 2.88 | .299 | 1.24 | 8.6 | 2.6 | 7.8 | 68.2 | 65 | 25 | 22 | 5 | 20 | 59 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 3.24 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 8 | 8 | 2 | 3 | 5.10 | .344 | 1.53 | 8.6 | 5.4 | 8.2 | 47.2 | 45 | 27 | 27 | 6 | 28 | 43 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 4.74 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 8 | 8 | 3 | 2 | 5.61 | .305 | 1.27 | 8.6 | 2.9 | 6.1 | 43.1 | 41 | 28 | 27 | 8 | 14 | 29 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 5.19 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 8 | 8 | 2 | 5 | 6.04 | .335 | 1.51 | 10.7 | 3.1 | 7.1 | 47.2 | 56 | 34 | 32 | 11 | 16 | 37 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 5.49 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 14 | 0 | 3 | 1 | 2.00 | .229 | 0.89 | 6.5 | 1.5 | 8.0 | 18.0 | 13 | 4 | 4 | 3 | 3 | 16 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 3.89 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 13 | 0 | 0 | 1 | 3.86 | .279 | 1.16 | 9.0 | 1.7 | 6.8 | 16.1 | 16 | 7 | 7 | 1 | 3 | 12 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 2.88 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 21 | 0 | 2 | 1 | 5.96 | .306 | 1.28 | 6.5 | 5.3 | 9.8 | 22.2 | 16 | 15 | 15 | 2 | 13 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 12 | 0 | 1 | 1 | 3.24 | .231 | 0.90 | 6.8 | 1.7 | 10.1 | 16.2 | 12 | 6 | 6 | 2 | 3 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.94 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 12 | 0 | 3 | 0 | 2.57 | .236 | 0.86 | 4.5 | 3.2 | 7.1 | 14.0 | 7 | 4 | 4 | 2 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 4.57 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 2 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | 18.0 | 0.0 | 0.0 | 1.1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 4 | 0 | 0 | 1 | 5.03 | .298 | 1.27 | 9.5 | 2.4 | 4.7 | 19.2 | 20 | 17 | 11 | 4 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.47 |