| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 22 | 22 | 10 | 4 | 2.82 | .273 | 1.11 | 6.4 | 3.7 | 8.7 | 143.2 | 101 | 47 | 45 | 11 | 59 | 139 | 0 | 0 | 0 | 0 | 18 | 2 | 1 | 3.34 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 21 | 21 | 6 | 12 | 4.34 | .284 | 1.18 | 7.7 | 3.0 | 4.8 | 147.1 | 125 | 75 | 71 | 18 | 49 | 78 | 7 | 0 | 0 | 2 | 11 | 1 | 2 | 4.55 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 20 | 20 | 8 | 5 | 4.42 | .334 | 1.50 | 9.4 | 4.1 | 5.9 | 132.1 | 138 | 67 | 65 | 18 | 60 | 87 | 1 | 0 | 0 | 0 | 11 | 1 | 0 | 4.84 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 21 | 20 | 8 | 10 | 4.36 | .319 | 1.40 | 9.0 | 3.6 | 6.0 | 142.1 | 142 | 75 | 69 | 17 | 57 | 94 | 4 | 0 | 0 | 2 | 9 | 1 | 6 | 4.46 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 93 | 42 | 0 | 3 | 8 | 3.74 | .312 | 1.34 | 5.9 | 6.3 | 10.5 | 43.1 | 28 | 18 | 18 | 3 | 30 | 50 | 0 | 17 | 3 | 0 | 0 | 1 | 1 | 3.74 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 49 | 0 | 1 | 2 | 3.10 | .308 | 1.24 | 6.1 | 5.1 | 6.2 | 49.1 | 33 | 17 | 17 | 5 | 28 | 34 | 0 | 3 | 3 | 0 | 0 | 5 | 4 | 4.96 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 37 | 0 | 1 | 1 | 1.85 | .278 | 1.13 | 5.8 | 4.4 | 6.0 | 39.0 | 25 | 8 | 8 | 1 | 19 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.54 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 22 | 0 | 1 | 1 | 4.38 | .267 | 1.09 | 6.8 | 3.4 | 8.6 | 24.2 | 18 | 12 | 12 | 6 | 9 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.46 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 9 | 0 | 0 | 1 | 5.50 | .335 | 1.51 | 11.4 | 2.4 | 4.6 | 37.2 | 47 | 25 | 23 | 4 | 10 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4.19 |