| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 9 | 9 | 2 | 7 | 7.28 | .356 | 1.60 | 10.1 | 4.2 | 6.9 | 47.0 | 53 | 41 | 38 | 10 | 22 | 36 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 5.83 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 8 | 8 | 2 | 4 | 7.41 | .342 | 1.50 | 10.3 | 3.2 | 5.3 | 34.0 | 39 | 28 | 28 | 5 | 12 | 20 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 4.97 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 8 | 8 | 3 | 3 | 6.80 | .362 | 1.68 | 10.9 | 4.3 | 7.5 | 42.1 | 51 | 32 | 32 | 6 | 20 | 35 | 0 | 0 | 0 | 0 | 2 | 1 | 2 | 4.69 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 8 | 8 | 2 | 5 | 6.63 | .394 | 1.92 | 12.8 | 4.5 | 6.2 | 38.0 | 54 | 35 | 28 | 6 | 19 | 26 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 5.26 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 23 | 0 | 1 | 0 | 4.73 | .310 | 1.35 | 10.7 | 1.7 | 9.3 | 26.2 | 31 | 18 | 14 | 4 | 5 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 21 | 0 | 1 | 0 | 2.22 | .255 | 1.03 | 6.4 | 3.0 | 9.8 | 24.1 | 17 | 8 | 6 | 2 | 8 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 82 | 19 | 0 | 0 | 0 | 6.43 | .344 | 1.57 | 9.4 | 4.7 | 8.6 | 21.0 | 22 | 15 | 15 | 7 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 11 | 0 | 1 | 0 | 4.20 | .384 | 1.87 | 13.2 | 3.6 | 6.0 | 15.0 | 22 | 7 | 7 | 1 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 11 | 0 | 1 | 0 | 6.10 | .404 | 2.03 | 9.9 | 9.0 | 13.5 | 10.1 | 11 | 7 | 7 | 0 | 10 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.00 |