| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 16 | 11 | 3.09 | .299 | 1.26 | 7.8 | 3.5 | 8.8 | 232.2 | 201 | 85 | 80 | 22 | 91 | 226 | 2 | 0 | 0 | 1 | 26 | 6 | 4 | 3.54 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 32 | 32 | 11 | 16 | 5.32 | .337 | 1.48 | 9.9 | 3.5 | 5.3 | 221.2 | 242 | 142 | 131 | 36 | 87 | 130 | 6 | 0 | 0 | 0 | 12 | 9 | 5 | 5.24 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 64 | 32 | 32 | 9 | 11 | 5.26 | .316 | 1.38 | 9.1 | 3.3 | 4.9 | 205.1 | 208 | 128 | 120 | 25 | 75 | 112 | 1 | 0 | 0 | 0 | 17 | 1 | 2 | 4.60 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 30 | 30 | 7 | 13 | 4.78 | .333 | 1.48 | 8.6 | 4.7 | 7.4 | 148.2 | 142 | 80 | 79 | 13 | 78 | 122 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.14 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 85 | 0 | 8 | 2 | 3.43 | .289 | 1.19 | 7.4 | 3.3 | 9.0 | 120.2 | 99 | 48 | 46 | 13 | 44 | 120 | 0 | 12 | 3 | 0 | 0 | 4 | 1 | 3.61 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 80 | 0 | 8 | 3 | 3.49 | .306 | 1.31 | 6.4 | 5.4 | 8.2 | 105.2 | 75 | 42 | 41 | 13 | 63 | 96 | 0 | 7 | 7 | 0 | 0 | 2 | 7 | 4.64 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 69 | 0 | 7 | 5 | 3.83 | .318 | 1.38 | 7.9 | 4.6 | 5.2 | 82.1 | 72 | 38 | 35 | 6 | 42 | 47 | 0 | 8 | 3 | 0 | 0 | 1 | 2 | 4.38 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 64 | 0 | 3 | 2 | 3.32 | .310 | 1.33 | 9.2 | 2.9 | 5.4 | 78.2 | 80 | 36 | 29 | 10 | 25 | 47 | 0 | 9 | 2 | 0 | 0 | 1 | 1 | 4.46 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 1 | 0 | 1 | 5.63 | .294 | 1.13 | 7.9 | 2.3 | 3.4 | 8.0 | 7 | 6 | 5 | 2 | 2 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 6.63 |
| SP | Sparks, T.Sparks, Tully >> | 32 | 1906 | R | 45 | 25 | 0 | 0 | 7 | 7.65 | .409 | 2.08 | 13.1 | 5.8 | 4.1 | 42.1 | 61 | 38 | 36 | 6 | 27 | 19 | 0 | 4 | 3 | 0 | 0 | 0 | 2 | 5.88 |