| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 34 | 34 | 10 | 15 | 3.66 | .289 | 1.18 | 8.4 | 2.2 | 5.4 | 219.0 | 205 | 99 | 89 | 17 | 53 | 131 | 6 | 0 | 0 | 3 | 20 | 9 | 3 | 3.66 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 33 | 33 | 9 | 17 | 6.69 | .363 | 1.71 | 10.9 | 4.5 | 5.3 | 141.1 | 171 | 108 | 105 | 21 | 70 | 83 | 0 | 0 | 0 | 0 | 11 | 1 | 6 | 5.27 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 70 | 31 | 31 | 10 | 11 | 5.17 | .343 | 1.54 | 10.7 | 3.2 | 8.6 | 188.0 | 223 | 112 | 108 | 28 | 66 | 180 | 1 | 0 | 0 | 0 | 12 | 5 | 4 | 4.15 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 80 | 0 | 6 | 4 | 4.44 | .326 | 1.41 | 9.9 | 2.8 | 8.1 | 105.1 | 115 | 54 | 52 | 11 | 33 | 94 | 0 | 0 | 3 | 0 | 0 | 5 | 0 | 3.66 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 65 | 0 | 4 | 4 | 4.14 | .343 | 1.55 | 8.3 | 5.7 | 11.7 | 76.0 | 70 | 35 | 35 | 8 | 48 | 99 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.70 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 67 | 0 | 3 | 1 | 2.99 | .309 | 1.33 | 7.9 | 4.1 | 7.9 | 75.1 | 66 | 25 | 25 | 7 | 34 | 66 | 0 | 1 | 0 | 0 | 0 | 1 | 7 | 3.85 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 65 | 0 | 1 | 4 | 4.34 | .302 | 1.30 | 7.8 | 4.0 | 10.8 | 66.1 | 57 | 32 | 32 | 10 | 29 | 79 | 0 | 31 | 3 | 0 | 0 | 0 | 1 | 3.89 |
| SU | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 48 | 0 | 2 | 5 | 4.46 | .329 | 1.46 | 9.9 | 3.3 | 6.4 | 68.2 | 75 | 38 | 34 | 7 | 25 | 48 | 0 | 2 | 4 | 0 | 0 | 1 | 3 | 4.07 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 8 | 0 | 0 | 0 | 3.77 | .306 | 1.33 | 8.4 | 3.9 | 10.3 | 14.1 | 13 | 6 | 6 | 1 | 6 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.93 |