| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 9 | 9 | 5 | 1 | 1.43 | .244 | 0.94 | 6.4 | 2.0 | 10.3 | 63.0 | 45 | 12 | 10 | 4 | 14 | 72 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 2.30 |
| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 8 | 8 | 4 | 3 | 3.08 | .270 | 1.04 | 7.5 | 1.9 | 5.5 | 61.1 | 51 | 21 | 21 | 3 | 13 | 37 | 2 | 0 | 0 | 0 | 6 | 4 | 3 | 3.26 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 8 | 8 | 2 | 5 | 5.74 | .356 | 1.62 | 11.7 | 2.9 | 8.2 | 47.0 | 61 | 31 | 30 | 7 | 15 | 43 | 1 | 0 | 0 | 0 | 4 | 2 | 1 | 4.19 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 85 | 8 | 8 | 4 | 0 | 4.11 | .271 | 1.09 | 6.8 | 3.1 | 8.5 | 50.1 | 38 | 24 | 23 | 8 | 17 | 47 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.28 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 21 | 0 | 2 | 2 | 2.45 | .221 | 0.85 | 5.0 | 2.8 | 9.0 | 29.1 | 16 | 9 | 8 | 2 | 9 | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.83 |