| SP | deGrom, J.deGrom, Jacob # $$ >> | 33 | 2021 | R | 100 | 22 | 22 | 10 | 6 | 3.19 | .254 | 1.01 | 6.7 | 2.4 | 9.2 | 144.0 | 107 | 52 | 51 | 17 | 39 | 147 | 1 | 0 | 0 | 1 | 17 | 1 | 0 | 3.33 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 7 | 6 | 5.04 | .314 | 1.36 | 9.4 | 2.9 | 5.6 | 141.0 | 147 | 82 | 79 | 21 | 45 | 87 | 2 | 0 | 0 | 0 | 8 | 2 | 2 | 4.70 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 20 | 20 | 7 | 4 | 5.20 | .301 | 1.27 | 8.7 | 2.7 | 6.9 | 126.1 | 122 | 74 | 73 | 16 | 38 | 96 | 0 | 0 | 0 | 0 | 11 | 3 | 3 | 4.10 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 21 | 20 | 8 | 8 | 5.33 | .316 | 1.37 | 9.2 | 3.2 | 5.5 | 138.1 | 141 | 85 | 82 | 25 | 49 | 84 | 4 | 1 | 0 | 0 | 7 | 2 | 0 | 5.25 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 63 | 0 | 8 | 3 | 2.57 | .252 | 1.00 | 5.3 | 3.7 | 10.9 | 91.0 | 54 | 27 | 26 | 7 | 37 | 110 | 0 | 7 | 3 | 0 | 0 | 1 | 7 | 2.84 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 52 | 0 | 5 | 4 | 3.53 | .287 | 1.21 | 7.4 | 3.6 | 9.6 | 63.2 | 52 | 25 | 25 | 7 | 25 | 67 | 0 | 9 | 2 | 0 | 0 | 0 | 0 | 3.51 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 39 | 0 | 7 | 2 | 2.61 | .268 | 1.08 | 7.5 | 2.3 | 10.3 | 48.1 | 40 | 14 | 14 | 2 | 12 | 55 | 0 | 5 | 1 | 0 | 0 | 1 | 2 | 2.06 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 29 | 0 | 1 | 2 | 4.28 | .344 | 1.54 | 10.1 | 4.1 | 9.0 | 33.2 | 37 | 19 | 16 | 6 | 15 | 33 | 0 | 6 | 1 | 0 | 0 | 1 | 9 | 4.82 |