| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 16 | 12 | 3.73 | .290 | 1.20 | 8.3 | 2.5 | 8.0 | 231.1 | 214 | 110 | 96 | 33 | 63 | 206 | 3 | 0 | 0 | 0 | 18 | 6 | 3 | 3.97 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 32 | 32 | 8 | 16 | 5.77 | .346 | 1.55 | 9.8 | 4.1 | 7.6 | 174.2 | 190 | 118 | 112 | 28 | 80 | 147 | 0 | 0 | 0 | 0 | 15 | 7 | 1 | 4.90 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 83 | 29 | 29 | 9 | 13 | 3.93 | .276 | 1.12 | 7.9 | 2.2 | 7.6 | 206.1 | 181 | 93 | 90 | 30 | 51 | 174 | 4 | 0 | 0 | 1 | 18 | 4 | 0 | 4.00 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 88 | 0 | 3 | 2 | 4.28 | .284 | 1.16 | 8.2 | 2.4 | 9.8 | 75.2 | 68 | 37 | 36 | 14 | 20 | 82 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 4.12 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 64 | 0 | 3 | 0 | 1.97 | .238 | 0.91 | 4.9 | 3.2 | 4.4 | 64.0 | 35 | 14 | 14 | 4 | 23 | 31 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 4.02 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 33 | 93 | 0 | 3 | 4 | 2.43 | .267 | 1.05 | 6.7 | 2.9 | 6.0 | 66.2 | 49 | 21 | 18 | 9 | 21 | 44 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 4.53 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 59 | 0 | 3 | 0 | 3.54 | .303 | 1.27 | 6.9 | 4.5 | 9.2 | 56.0 | 43 | 22 | 22 | 8 | 28 | 57 | 0 | 1 | 1 | 0 | 0 | 2 | 4 | 4.43 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 12 | 2 | 3 | 3 | 5.40 | .340 | 1.54 | 9.4 | 4.7 | 8.2 | 23.1 | 24 | 14 | 14 | 2 | 12 | 21 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 3.87 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 63 | 0 | 1 | 5 | 2.26 | .251 | 1.01 | 5.9 | 3.3 | 8.6 | 63.2 | 41 | 17 | 16 | 3 | 23 | 60 | 0 | 38 | 6 | 0 | 0 | 0 | 3 | 2.81 |