| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 84 | 36 | 36 | 11 | 16 | 5.90 | .340 | 1.51 | 10.3 | 3.3 | 7.1 | 225.2 | 257 | 151 | 148 | 50 | 83 | 177 | 4 | 0 | 0 | 1 | 14 | 9 | 5 | 5.54 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 82 | 36 | 36 | 14 | 16 | 5.38 | .334 | 1.48 | 9.7 | 3.6 | 6.2 | 232.2 | 251 | 150 | 139 | 45 | 93 | 161 | 10 | 0 | 0 | 2 | 14 | 6 | 2 | 5.41 |
| SP | Skubal, T.Skubal, Tarik >> | 27 | 2024 | L | 79 | 34 | 34 | 11 | 12 | 5.49 | .330 | 1.47 | 10.1 | 3.1 | 9.5 | 200.0 | 224 | 130 | 122 | 40 | 69 | 211 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 4.56 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 66 | 32 | 32 | 15 | 10 | 4.11 | .322 | 1.40 | 8.8 | 3.8 | 8.5 | 206.0 | 201 | 96 | 94 | 38 | 87 | 195 | 2 | 0 | 0 | 1 | 17 | 6 | 2 | 4.86 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 56 | 24 | 24 | 6 | 10 | 7.32 | .348 | 1.58 | 10.5 | 3.7 | 9.7 | 123.0 | 144 | 104 | 100 | 33 | 50 | 132 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 5.63 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 55 | 82 | 0 | 7 | 3 | 3.63 | .280 | 1.14 | 6.6 | 3.7 | 9.0 | 114.0 | 83 | 46 | 46 | 13 | 47 | 114 | 0 | 4 | 5 | 0 | 0 | 3 | 0 | 3.80 |
| RP | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 64 | 76 | 0 | 5 | 6 | 4.14 | .311 | 1.33 | 9.9 | 2.1 | 5.8 | 111.0 | 122 | 54 | 51 | 10 | 26 | 71 | 0 | 12 | 5 | 0 | 0 | 2 | 0 | 3.65 |
| RP | Fister, D.Fister, Doug >> | 27 | 2011 | R | 29 | 51 | 0 | 3 | 7 | 3.20 | .274 | 1.12 | 8.6 | 1.4 | 5.6 | 76.0 | 73 | 32 | 27 | 12 | 12 | 47 | 0 | 8 | 1 | 0 | 0 | 1 | 0 | 4.33 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 23 | 11 | 0 | 0 | 1 | 4.05 | .355 | 1.65 | 9.0 | 6.2 | 6.9 | 13.1 | 13 | 6 | 6 | 2 | 9 | 10 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 5.54 |
| RP | Turnbull, S.Turnbull, Spencer >> | 28 | 2021 | R | 2 | 5 | 0 | 0 | 1 | 12.46 | .447 | 2.42 | 13.5 | 10.1 | 10.1 | 8.2 | 12 | 12 | 12 | 2 | 9 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.38 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 15 | 8 | 0 | 1 | 0 | 0.00 | .245 | 0.98 | 7.6 | 1.4 | 6.9 | 13.1 | 11 | 0 | 0 | 0 | 2 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.92 |
| SP | Wilson, E.Wilson, Earl >> | 32 | 1966 | R | 28 | 19 | 0 | 3 | 4 | 5.38 | .328 | 1.46 | 9.6 | 3.6 | 6.5 | 90.1 | 96 | 61 | 54 | 14 | 36 | 65 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 4.78 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 7 | 19 | 0 | 0 | 0 | 2.62 | .264 | 1.05 | 7.9 | 1.6 | 6.9 | 34.1 | 30 | 13 | 10 | 3 | 6 | 26 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.24 |