| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 27 | 5 | 12 | 5.92 | .341 | 1.52 | 9.9 | 3.9 | 8.3 | 135.1 | 148 | 92 | 89 | 23 | 58 | 124 | 1 | 0 | 0 | 1 | 10 | 4 | 3 | 4.76 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 25 | 25 | 10 | 7 | 3.71 | .287 | 1.19 | 8.0 | 2.7 | 6.9 | 179.2 | 160 | 75 | 74 | 18 | 54 | 138 | 5 | 0 | 0 | 3 | 16 | 3 | 0 | 3.72 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 26 | 26 | 9 | 12 | 4.38 | .317 | 1.38 | 8.6 | 3.9 | 4.4 | 168.1 | 160 | 85 | 82 | 19 | 72 | 83 | 6 | 0 | 0 | 2 | 13 | 2 | 1 | 4.80 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 25 | 25 | 7 | 12 | 4.33 | .298 | 1.26 | 8.2 | 3.2 | 5.4 | 153.2 | 139 | 82 | 74 | 15 | 55 | 92 | 1 | 0 | 0 | 0 | 14 | 2 | 8 | 4.19 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 24 | 24 | 9 | 10 | 4.47 | .290 | 1.22 | 8.2 | 2.9 | 4.1 | 161.0 | 146 | 81 | 80 | 17 | 51 | 74 | 9 | 0 | 0 | 2 | 9 | 0 | 1 | 4.40 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 69 | 0 | 5 | 8 | 3.94 | .296 | 1.25 | 8.6 | 2.7 | 8.4 | 93.2 | 89 | 42 | 41 | 8 | 28 | 87 | 0 | 5 | 6 | 0 | 0 | 1 | 1 | 3.18 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 60 | 0 | 4 | 2 | 3.61 | .324 | 1.44 | 7.5 | 5.5 | 11.0 | 67.1 | 56 | 28 | 27 | 10 | 41 | 82 | 0 | 4 | 1 | 0 | 0 | 0 | 4 | 4.33 |
| RP | Niedenfuer, T.Niedenfuer, Tom † >> | 24 | 1983 | R | 62 | 46 | 0 | 4 | 2 | 2.77 | .270 | 1.05 | 5.7 | 3.8 | 6.0 | 68.1 | 43 | 21 | 21 | 4 | 29 | 45 | 0 | 6 | 0 | 0 | 0 | 4 | 0 | 3.90 |
| RP | Smoltz, J.Smoltz, John # >> | 36 | 2003 | R | 52 | 36 | 0 | 1 | 2 | 6.15 | .377 | 1.75 | 12.8 | 3.3 | 7.6 | 33.2 | 47 | 25 | 23 | 5 | 12 | 28 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.55 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 45 | 30 | 0 | 2 | 2 | 2.79 | .242 | 0.96 | 5.4 | 3.3 | 12.6 | 38.2 | 23 | 15 | 12 | 7 | 14 | 53 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.71 |