| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 100 | 19 | 19 | 9 | 6 | 3.94 | .294 | 1.22 | 8.9 | 2.1 | 9.2 | 130.1 | 128 | 57 | 57 | 14 | 31 | 133 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 3.16 |
| SP | McGowan, D.McGowan, Dustin >> | 25 | 2007 | R | 79 | 18 | 18 | 3 | 7 | 5.08 | .319 | 1.40 | 8.5 | 4.1 | 6.3 | 111.2 | 105 | 66 | 63 | 11 | 51 | 78 | 0 | 0 | 0 | 0 | 6 | 1 | 8 | 4.29 |
| SP | Hernandez, F.Hernandez, Felix >> | 29 | 2015 | R | 77 | 18 | 18 | 9 | 6 | 5.03 | .328 | 1.45 | 9.5 | 3.6 | 6.7 | 105.2 | 111 | 61 | 59 | 11 | 42 | 78 | 1 | 0 | 0 | 0 | 10 | 2 | 4 | 4.13 |
| RP | Poche, C.Poche, Colin # >> | 28 | 2022 | L | 83 | 50 | 0 | 3 | 2 | 4.59 | .305 | 1.28 | 7.6 | 4.1 | 10.1 | 64.2 | 54 | 34 | 33 | 12 | 29 | 72 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 4.64 |
| RP | Raley, B.Raley, Brooks >> | 33 | 2021 | L | 69 | 47 | 0 | 2 | 0 | 3.13 | .320 | 1.37 | 10.2 | 2.2 | 8.4 | 46.0 | 52 | 19 | 16 | 3 | 11 | 43 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 2.83 |
| RP | Blevins, J.Blevins, Jerry >> | 31 | 2014 | L | 67 | 34 | 0 | 3 | 0 | 2.92 | .279 | 1.16 | 5.4 | 5.1 | 8.5 | 37.0 | 22 | 13 | 12 | 3 | 21 | 35 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.86 |
| RP | Hendriks, L.Hendriks, Liam >> | 28 | 2017 | R | 63 | 18 | 0 | 0 | 0 | 3.86 | .333 | 1.45 | 10.0 | 3.5 | 5.0 | 18.2 | 20 | 9 | 8 | 3 | 7 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 5 | 5.39 |