| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 32 | 32 | 16 | 11 | 3.19 | .280 | 1.14 | 7.7 | 2.5 | 7.5 | 234.1 | 200 | 89 | 83 | 20 | 66 | 195 | 6 | 0 | 0 | 1 | 22 | 7 | 5 | 3.38 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 31 | 28 | 26 | 12 | 10 | 5.21 | .338 | 1.50 | 9.0 | 4.5 | 6.3 | 171.0 | 171 | 102 | 99 | 15 | 85 | 119 | 0 | 0 | 0 | 0 | 11 | 6 | 5 | 4.35 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 23 | 13 | 6 | 5 | 4.87 | .345 | 1.55 | 10.1 | 3.9 | 7.3 | 118.1 | 133 | 66 | 64 | 14 | 51 | 96 | 0 | 0 | 0 | 0 | 4 | 3 | 3 | 4.29 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 29 | 6 | 11 | 4.67 | .331 | 1.45 | 9.2 | 3.9 | 5.5 | 187.0 | 191 | 102 | 97 | 14 | 80 | 115 | 2 | 1 | 0 | 0 | 17 | 6 | 2 | 4.12 |
| SU | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 22 | 0 | 2 | 2 | 2.35 | .274 | 1.09 | 5.1 | 4.7 | 7.0 | 23.0 | 13 | 6 | 6 | 1 | 12 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.70 |
| CL | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 56 | 0 | 2 | 0 | 0.91 | .209 | 0.79 | 5.2 | 2.0 | 8.7 | 59.1 | 34 | 8 | 6 | 1 | 13 | 57 | 0 | 19 | 2 | 0 | 0 | 0 | 6 | 1.95 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 22 | 0 | 1 | 1 | 5.14 | .357 | 1.62 | 13.3 | 1.3 | 6.9 | 21.0 | 31 | 15 | 12 | 4 | 3 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.52 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 17 | 0 | 2 | 0 | 3.20 | .224 | 0.87 | 3.6 | 4.3 | 9.0 | 25.1 | 10 | 9 | 9 | 4 | 12 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.52 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 36 | 0 | 1 | 1 | 3.93 | .247 | 0.93 | 6.5 | 2.0 | 9.3 | 36.2 | 26 | 19 | 16 | 5 | 8 | 37 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 3.58 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 47 | 0 | 0 | 8 | 4.76 | .317 | 1.39 | 9.2 | 3.4 | 9.2 | 45.1 | 46 | 25 | 24 | 9 | 17 | 46 | 0 | 25 | 4 | 0 | 0 | 0 | 1 | 4.69 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 31 | 22 | 14 | 10 | 4.52 | .324 | 1.41 | 8.7 | 4.0 | 5.4 | 183.0 | 176 | 95 | 92 | 24 | 82 | 110 | 1 | 0 | 0 | 0 | 8 | 5 | 2 | 4.93 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 31 | 0 | 2 | 3 | 3.64 | .264 | 1.04 | 6.2 | 3.4 | 7.1 | 29.2 | 20 | 13 | 12 | 3 | 11 | 23 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.00 |