| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 23 | 23 | 7 | 9 | 3.76 | .290 | 1.20 | 8.3 | 2.5 | 6.7 | 167.1 | 154 | 75 | 70 | 20 | 47 | 125 | 6 | 0 | 0 | 2 | 12 | 4 | 1 | 3.98 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 22 | 22 | 9 | 8 | 3.71 | .293 | 1.21 | 8.1 | 2.8 | 5.3 | 165.0 | 149 | 81 | 68 | 15 | 51 | 97 | 5 | 0 | 0 | 2 | 14 | 5 | 2 | 4.02 |
| SP | Reulbach, E.Reulbach, Ed # >> | 24 | 1906 | R | 61 | 20 | 20 | 10 | 4 | 4.12 | .309 | 1.31 | 7.4 | 4.4 | 4.1 | 131.0 | 107 | 62 | 60 | 13 | 64 | 60 | 2 | 0 | 0 | 1 | 11 | 5 | 3 | 4.95 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 56 | 0 | 3 | 0 | 1.12 | .233 | 0.87 | 4.5 | 3.4 | 11.6 | 48.1 | 24 | 6 | 6 | 5 | 18 | 62 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.02 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 55 | 0 | 7 | 5 | 3.33 | .256 | 1.01 | 7.6 | 1.6 | 8.1 | 51.1 | 43 | 21 | 19 | 10 | 9 | 46 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.33 |
| CL | Hoffman, T.Hoffman, Trevor † >> | 31 | 1998 | R | 75 | 41 | 0 | 1 | 0 | 2.58 | .294 | 1.17 | 7.3 | 3.3 | 6.9 | 38.1 | 31 | 15 | 11 | 1 | 14 | 29 | 0 | 32 | 4 | 0 | 0 | 3 | 2 | 3.16 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 24 | 0 | 4 | 4 | 5.31 | .322 | 1.38 | 8.6 | 4.1 | 9.9 | 20.1 | 19 | 13 | 12 | 2 | 9 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.60 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 14 | 0 | 3 | 1 | 2.25 | .226 | 0.88 | 6.2 | 1.7 | 9.0 | 16.0 | 11 | 6 | 4 | 1 | 3 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.38 |
| SP | Jenkins, F.Jenkins, Fergie >> | 29 | 1971 | R | 15 | 11 | 1 | 0 | 0 | 4.40 | .295 | 1.26 | 9.2 | 2.1 | 4.4 | 43.0 | 44 | 26 | 21 | 4 | 10 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.93 |