| SP | McNally, D.McNally, Dave † # >> | 26 | 1968 | L | 96 | 23 | 23 | 9 | 9 | 3.96 | .271 | 1.08 | 7.8 | 2.0 | 5.5 | 186.1 | 161 | 86 | 82 | 25 | 41 | 113 | 8 | 0 | 0 | 1 | 12 | 6 | 0 | 4.29 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 22 | 22 | 6 | 14 | 6.48 | .369 | 1.74 | 11.6 | 4.0 | 5.0 | 150.0 | 194 | 114 | 108 | 19 | 67 | 83 | 3 | 0 | 0 | 0 | 5 | 2 | 4 | 4.92 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 21 | 21 | 4 | 11 | 5.14 | .335 | 1.48 | 10.0 | 3.3 | 4.7 | 143.2 | 159 | 89 | 82 | 20 | 53 | 74 | 2 | 0 | 0 | 0 | 8 | 5 | 3 | 5.00 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 21 | 21 | 7 | 10 | 5.90 | .352 | 1.60 | 10.7 | 3.8 | 5.5 | 151.0 | 179 | 107 | 99 | 14 | 63 | 92 | 6 | 0 | 0 | 1 | 5 | 4 | 2 | 4.32 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 59 | 0 | 6 | 3 | 2.53 | .251 | 0.98 | 6.0 | 2.9 | 9.1 | 74.2 | 49 | 24 | 21 | 5 | 24 | 75 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 2.91 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 48 | 0 | 2 | 5 | 4.37 | .321 | 1.42 | 8.8 | 4.0 | 5.6 | 47.1 | 46 | 26 | 23 | 5 | 21 | 29 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 4.49 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 22 | 0 | 3 | 0 | 5.47 | .333 | 1.50 | 7.9 | 6.0 | 7.9 | 24.2 | 21 | 15 | 15 | 2 | 16 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 17 | 0 | 3 | 1 | 5.95 | .359 | 1.68 | 13.3 | 2.4 | 8.1 | 19.2 | 28 | 13 | 13 | 3 | 5 | 17 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.05 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 46 | 15 | 0 | 0 | 0 | 3.50 | .308 | 1.28 | 7.5 | 4.0 | 4.5 | 18.0 | 15 | 7 | 7 | 3 | 8 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.67 |