| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 31 | 31 | 11 | 11 | 3.76 | .292 | 1.22 | 7.6 | 3.3 | 8.3 | 215.1 | 182 | 93 | 90 | 22 | 80 | 199 | 1 | 0 | 0 | 1 | 18 | 4 | 4 | 3.65 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 31 | 31 | 9 | 19 | 5.51 | .361 | 1.66 | 10.9 | 4.1 | 5.6 | 214.0 | 259 | 140 | 131 | 30 | 97 | 134 | 8 | 0 | 0 | 0 | 10 | 6 | 10 | 5.01 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 31 | 31 | 12 | 15 | 5.50 | .355 | 1.63 | 10.8 | 3.8 | 4.5 | 206.0 | 247 | 132 | 126 | 25 | 88 | 103 | 2 | 0 | 0 | 0 | 13 | 5 | 5 | 4.93 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 60 | 29 | 29 | 8 | 10 | 5.36 | .313 | 1.35 | 8.6 | 3.5 | 6.3 | 193.0 | 185 | 121 | 115 | 40 | 75 | 136 | 4 | 0 | 0 | 0 | 13 | 4 | 12 | 5.51 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 80 | 0 | 8 | 2 | 2.65 | .311 | 1.32 | 7.5 | 4.4 | 10.4 | 119.0 | 99 | 39 | 35 | 11 | 58 | 138 | 0 | 10 | 4 | 0 | 0 | 4 | 0 | 3.45 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 1 | 1 | 1 | 0 | 3.68 | .389 | 1.91 | 15.4 | 2.6 | 5.1 | 7.1 | 12 | 3 | 3 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.57 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 1 | 1 | 1 | 0 | 1.50 | .308 | 1.17 | 7.5 | 3.0 | 6.0 | 6.0 | 5 | 1 | 1 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.33 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 43 | 15 | 0 | 2 | 3 | 2.45 | .290 | 1.23 | 9.0 | 2.0 | 5.3 | 22.0 | 22 | 6 | 6 | 1 | 5 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.09 |