| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 21 | 21 | 8 | 7 | 3.10 | .289 | 1.20 | 7.1 | 3.8 | 6.2 | 136.1 | 107 | 53 | 47 | 9 | 57 | 94 | 2 | 0 | 0 | 1 | 16 | 2 | 0 | 3.78 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 6 | 6 | 3.95 | .288 | 1.17 | 7.7 | 2.8 | 5.6 | 132.0 | 113 | 61 | 58 | 19 | 41 | 82 | 2 | 0 | 0 | 1 | 12 | 6 | 2 | 4.70 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 19 | 19 | 8 | 6 | 4.87 | .323 | 1.41 | 8.9 | 3.9 | 4.8 | 114.2 | 113 | 64 | 62 | 12 | 49 | 61 | 1 | 0 | 0 | 1 | 8 | 2 | 3 | 4.64 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 20 | 19 | 9 | 5 | 3.88 | .277 | 1.13 | 7.6 | 2.6 | 3.8 | 132.1 | 112 | 57 | 57 | 13 | 38 | 55 | 0 | 0 | 0 | 0 | 12 | 2 | 3 | 4.36 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 56 | 0 | 3 | 2 | 3.21 | .287 | 1.16 | 6.8 | 3.7 | 10.1 | 73.0 | 55 | 26 | 26 | 4 | 30 | 82 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 2.82 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 47 | 0 | 3 | 4 | 3.32 | .290 | 1.19 | 7.5 | 3.4 | 6.6 | 59.2 | 49 | 23 | 22 | 6 | 22 | 43 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 4.08 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 42 | 0 | 4 | 1 | 2.98 | .249 | 0.99 | 6.2 | 2.8 | 9.9 | 51.1 | 35 | 17 | 17 | 4 | 16 | 56 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 2.76 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 30 | 0 | 2 | 1 | 1.38 | .274 | 1.13 | 6.2 | 4.2 | 8.2 | 32.2 | 22 | 5 | 5 | 0 | 15 | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.59 |