| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 34 | 34 | 14 | 14 | 3.56 | .278 | 1.14 | 7.9 | 2.4 | 8.0 | 270.1 | 236 | 115 | 107 | 32 | 72 | 239 | 14 | 0 | 0 | 2 | 22 | 5 | 5 | 3.63 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 33 | 33 | 9 | 12 | 4.69 | .306 | 1.32 | 8.6 | 3.3 | 8.5 | 209.1 | 200 | 118 | 109 | 30 | 76 | 198 | 1 | 0 | 0 | 1 | 17 | 1 | 6 | 4.08 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 32 | 8 | 17 | 5.80 | .336 | 1.48 | 10.2 | 3.2 | 5.7 | 235.2 | 266 | 158 | 152 | 31 | 83 | 149 | 11 | 0 | 0 | 0 | 7 | 9 | 8 | 4.62 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 31 | 31 | 9 | 17 | 5.27 | .343 | 1.55 | 10.5 | 3.5 | 5.8 | 218.2 | 254 | 136 | 128 | 32 | 85 | 140 | 7 | 0 | 0 | 0 | 12 | 3 | 9 | 4.83 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 31 | 31 | 10 | 14 | 3.91 | .335 | 1.51 | 9.4 | 4.2 | 5.0 | 216.1 | 226 | 103 | 94 | 16 | 100 | 119 | 4 | 0 | 0 | 1 | 16 | 1 | 3 | 4.26 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 84 | 0 | 5 | 9 | 3.98 | .293 | 1.22 | 6.4 | 4.7 | 8.9 | 117.2 | 83 | 53 | 52 | 14 | 61 | 116 | 0 | 13 | 7 | 0 | 0 | 2 | 0 | 4.19 |
| RP | Wilhelm, H.Wilhelm, Hoyt # >> | 43 | 1965 | R | 69 | 57 | 0 | 6 | 9 | 5.62 | .315 | 1.38 | 8.9 | 3.6 | 4.3 | 91.1 | 90 | 58 | 57 | 22 | 36 | 43 | 0 | 6 | 6 | 0 | 0 | 0 | 2 | 6.38 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 22 | 0 | 1 | 0 | 3.71 | .310 | 1.35 | 7.3 | 5.2 | 8.0 | 26.2 | 21 | 11 | 11 | 3 | 15 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 4.46 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 55 | 1 | 1 | 0 | 1 | 3.86 | .400 | 2.00 | 7.7 | 10.3 | 11.6 | 7.0 | 6 | 3 | 3 | 1 | 8 | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.71 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 11 | 0 | 2 | 3 | 5.68 | .329 | 1.42 | 9.0 | 3.8 | 9.0 | 19.0 | 19 | 12 | 12 | 1 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.11 |