| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 98 | 23 | 23 | 11 | 9 | 3.20 | .278 | 1.12 | 7.3 | 2.8 | 7.8 | 183.0 | 149 | 73 | 65 | 18 | 56 | 158 | 11 | 0 | 0 | 3 | 15 | 6 | 6 | 3.57 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 84 | 22 | 22 | 9 | 12 | 3.87 | .273 | 1.09 | 7.9 | 2.0 | 3.0 | 162.2 | 142 | 73 | 70 | 21 | 36 | 54 | 5 | 0 | 0 | 3 | 10 | 5 | 6 | 4.78 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 21 | 21 | 6 | 12 | 6.85 | .371 | 1.74 | 12.1 | 3.6 | 4.4 | 114.1 | 153 | 93 | 87 | 24 | 46 | 56 | 1 | 0 | 0 | 0 | 9 | 3 | 9 | 6.04 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 21 | 21 | 9 | 10 | 4.67 | .317 | 1.36 | 9.3 | 3.1 | 8.5 | 140.2 | 144 | 79 | 73 | 22 | 48 | 132 | 2 | 0 | 0 | 0 | 12 | 4 | 1 | 4.27 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 55 | 0 | 2 | 2 | 3.11 | .277 | 1.14 | 6.4 | 3.8 | 9.1 | 81.0 | 58 | 30 | 28 | 10 | 34 | 82 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 3.88 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 44 | 0 | 4 | 2 | 2.73 | .255 | 0.99 | 5.3 | 3.7 | 7.5 | 59.1 | 35 | 18 | 18 | 4 | 24 | 49 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 3.54 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 28 | 0 | 3 | 4 | 3.67 | .316 | 1.37 | 7.9 | 4.4 | 4.4 | 49.0 | 43 | 23 | 20 | 6 | 24 | 24 | 0 | 1 | 2 | 0 | 0 | 1 | 3 | 5.14 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 2 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 12 | 0 | 1 | 0 | 6.53 | .347 | 1.60 | 9.0 | 5.9 | 9.0 | 20.2 | 20 | 15 | 15 | 5 | 13 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.20 |