| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 7 | 7 | 3 | 4 | 3.91 | .277 | 1.13 | 8.3 | 1.9 | 5.3 | 53.0 | 49 | 23 | 23 | 5 | 11 | 31 | 3 | 0 | 0 | 0 | 5 | 1 | 0 | 3.74 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 7 | 7 | 0 | 2 | 10.61 | .429 | 2.25 | 16.1 | 4.2 | 5.5 | 28.0 | 50 | 33 | 33 | 6 | 13 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.96 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 7 | 7 | 3 | 3 | 4.47 | .308 | 1.34 | 9.6 | 2.5 | 3.7 | 46.1 | 49 | 25 | 23 | 7 | 13 | 19 | 1 | 0 | 0 | 1 | 3 | 0 | 1 | 5.00 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 8 | 7 | 2 | 4 | 7.64 | .376 | 1.73 | 10.5 | 5.1 | 5.7 | 35.1 | 41 | 30 | 30 | 4 | 20 | 22 | 1 | 0 | 0 | 0 | 2 | 3 | 1 | 5.20 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 19 | 0 | 2 | 0 | 2.22 | .248 | 0.92 | 5.8 | 2.6 | 9.0 | 28.1 | 18 | 7 | 7 | 1 | 8 | 28 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 2.54 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 19 | 0 | 2 | 0 | 6.84 | .352 | 1.59 | 10.4 | 4.2 | 7.6 | 26.1 | 30 | 20 | 20 | 6 | 12 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 5.81 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 19 | 0 | 1 | 1 | 1.59 | .306 | 1.24 | 8.2 | 3.3 | 10.2 | 22.2 | 20 | 4 | 4 | 2 | 8 | 25 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.27 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 15 | 0 | 1 | 2 | 7.23 | .317 | 1.34 | 8.5 | 4.0 | 9.0 | 18.2 | 17 | 15 | 15 | 4 | 8 | 18 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.39 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 10 | 0 | 0 | 0 | 6.75 | .347 | 1.59 | 13.5 | 1.8 | 5.4 | 10.2 | 15 | 10 | 8 | 5 | 2 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.90 |