| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 32 | 32 | 10 | 11 | 4.38 | .290 | 1.21 | 8.5 | 2.5 | 8.9 | 207.2 | 195 | 105 | 101 | 32 | 57 | 204 | 0 | 0 | 0 | 0 | 19 | 3 | 0 | 3.91 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 31 | 31 | 6 | 6 | 4.09 | .324 | 1.42 | 9.4 | 3.4 | 4.9 | 167.1 | 174 | 85 | 76 | 23 | 64 | 91 | 0 | 0 | 0 | 0 | 10 | 3 | 4 | 4.90 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 31 | 31 | 16 | 8 | 4.14 | .297 | 1.25 | 8.0 | 3.3 | 7.6 | 232.1 | 205 | 116 | 107 | 20 | 85 | 195 | 5 | 0 | 0 | 1 | 18 | 4 | 2 | 3.59 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 29 | 29 | 12 | 14 | 5.43 | .339 | 1.52 | 10.8 | 2.9 | 4.6 | 215.1 | 257 | 132 | 130 | 26 | 70 | 111 | 8 | 0 | 0 | 1 | 10 | 5 | 4 | 4.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 71 | 0 | 9 | 3 | 3.80 | .271 | 1.07 | 7.4 | 2.2 | 8.7 | 97.0 | 80 | 41 | 41 | 8 | 24 | 94 | 0 | 8 | 4 | 0 | 0 | 4 | 1 | 3.00 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 67 | 0 | 8 | 6 | 3.86 | .302 | 1.25 | 7.3 | 4.0 | 6.3 | 81.2 | 66 | 38 | 35 | 11 | 36 | 57 | 0 | 10 | 6 | 0 | 0 | 4 | 1 | 4.84 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 52 | 33 | 0 | 1 | 2 | 2.98 | .277 | 1.15 | 7.4 | 3.0 | 6.8 | 45.1 | 37 | 15 | 15 | 3 | 15 | 34 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.36 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 52 | 9 | 0 | 1 | 3 | 3.45 | .338 | 1.53 | 11.4 | 3.0 | 4.2 | 15.2 | 19 | 6 | 6 | 2 | 5 | 7 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.80 |