| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 33 | 33 | 17 | 6 | 3.59 | .295 | 1.23 | 8.0 | 3.1 | 7.8 | 198.0 | 176 | 80 | 79 | 22 | 68 | 171 | 1 | 0 | 0 | 1 | 21 | 4 | 1 | 3.81 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 31 | 31 | 15 | 9 | 3.28 | .280 | 1.14 | 6.8 | 3.5 | 4.9 | 197.1 | 148 | 77 | 72 | 17 | 76 | 107 | 2 | 0 | 0 | 0 | 21 | 6 | 2 | 4.28 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 84 | 31 | 31 | 16 | 10 | 3.96 | .293 | 1.23 | 8.5 | 2.6 | 7.7 | 211.1 | 200 | 93 | 93 | 25 | 60 | 180 | 5 | 0 | 0 | 1 | 18 | 3 | 2 | 3.73 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 79 | 0 | 6 | 0 | 2.30 | .251 | 0.98 | 5.7 | 3.1 | 9.3 | 109.2 | 69 | 29 | 28 | 6 | 38 | 113 | 0 | 15 | 3 | 0 | 0 | 3 | 2 | 2.77 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 70 | 0 | 5 | 3 | 3.14 | .259 | 1.03 | 7.4 | 1.9 | 8.0 | 86.0 | 71 | 31 | 30 | 8 | 18 | 76 | 0 | 12 | 4 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 32 | 0 | 2 | 1 | 3.17 | .312 | 1.33 | 8.3 | 3.7 | 8.6 | 65.1 | 60 | 25 | 23 | 11 | 27 | 62 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.63 |