| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 23 | 23 | 15 | 5 | 3.02 | .284 | 1.18 | 8.5 | 2.0 | 5.8 | 176.0 | 167 | 66 | 59 | 15 | 40 | 113 | 5 | 0 | 0 | 2 | 17 | 2 | 3 | 3.54 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 45 | 20 | 20 | 4 | 13 | 6.06 | .371 | 1.74 | 10.2 | 5.5 | 8.2 | 108.1 | 122 | 81 | 73 | 14 | 66 | 98 | 0 | 0 | 0 | 0 | 9 | 4 | 6 | 4.81 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 49 | 0 | 4 | 2 | 2.60 | .297 | 1.25 | 6.7 | 4.6 | 9.4 | 62.1 | 46 | 19 | 18 | 4 | 32 | 65 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.34 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 29 | 0 | 2 | 1 | 2.60 | .283 | 1.15 | 6.4 | 4.2 | 8.7 | 34.2 | 24 | 10 | 10 | 3 | 16 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 18 | 0 | 1 | 1 | 4.42 | .304 | 1.25 | 9.0 | 2.5 | 8.0 | 18.1 | 18 | 9 | 9 | 2 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 10 | 0 | 0 | 3 | 9.31 | .356 | 1.66 | 9.0 | 7.0 | 6.0 | 9.2 | 9 | 10 | 10 | 2 | 7 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.89 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 17 | 0 | 0 | 0 | 3.57 | .293 | 1.13 | 6.4 | 4.2 | 9.5 | 17.2 | 12 | 8 | 7 | 3 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.94 |