| SP | Koosman, J.Koosman, Jerry >> | 34 | 1976 | L | 92 | 6 | 6 | 2 | 2 | 3.55 | .325 | 1.42 | 9.4 | 3.6 | 5.4 | 45.2 | 47 | 18 | 18 | 1 | 18 | 27 | 1 | 0 | 0 | 1 | 4 | 1 | 2 | 3.36 |
| SP | Johnson, R.Johnson, Randy >> | 29 | 1992 | L | 62 | 6 | 6 | 0 | 4 | 9.11 | .432 | 2.28 | 12.3 | 8.7 | 8.0 | 27.2 | 37 | 28 | 28 | 3 | 26 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.56 |
| SP | Germano, J.Germano, Justin >> | 25 | 2007 | R | 48 | 6 | 6 | 1 | 1 | 5.74 | .370 | 1.76 | 12.1 | 4.2 | 6.2 | 26.2 | 35 | 21 | 17 | 3 | 12 | 18 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.50 |
| SP | Marquis, J.Marquis, Jason # >> | 29 | 2007 | R | 41 | 6 | 6 | 2 | 2 | 5.08 | .318 | 1.37 | 9.0 | 3.5 | 6.3 | 33.2 | 33 | 19 | 19 | 6 | 13 | 23 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.24 |
| RP | Robles, H.Robles, Hansel >> | 24 | 2015 | R | 94 | 12 | 0 | 2 | 0 | 1.59 | .261 | 1.06 | 5.3 | 4.2 | 9.5 | 17.0 | 10 | 3 | 3 | 1 | 8 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.06 |
| RP | Service, S.Service, Scott >> | 26 | 1993 | R | 42 | 17 | 0 | 1 | 1 | 3.90 | .231 | 0.90 | 6.7 | 1.7 | 6.3 | 27.2 | 20 | 12 | 12 | 8 | 5 | 19 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Perez, O.Perez, Oliver >> | 35 | 2016 | L | 29 | 9 | 0 | 2 | 1 | 1.88 | .246 | 0.98 | 6.4 | 2.6 | 13.5 | 14.1 | 10 | 3 | 3 | 1 | 4 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 1.79 |
| SP | Swindell, G.Swindell, Greg >> | 28 | 1993 | L | 34 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Pettitte, A.Pettitte, Andy >> | 35 | 2007 | L | 27 | 3 | 0 | 0 | 0 | 4.15 | .235 | 0.92 | 9.0 | 0.0 | 9.0 | 4.1 | 4 | 2 | 2 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.25 |
| SP | Mikolas, M.Mikolas, Miles >> | 36 | 2025 | R | 39 | 11 | 0 | 1 | 4 | 8.66 | .411 | 2.09 | 16.9 | 2.6 | 5.8 | 17.2 | 32 | 17 | 17 | 4 | 5 | 11 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 5.65 |