| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 100 | 10 | 10 | 1 | 4 | 7.89 | .398 | 1.96 | 12.3 | 5.4 | 6.9 | 43.1 | 59 | 39 | 38 | 7 | 26 | 33 | 1 | 0 | 0 | 0 | 2 | 1 | 2 | 5.47 |
| SP | Schmitz, J.Schmitz, Johnny >> | 28 | 1948 | L | 84 | 10 | 10 | 5 | 2 | 3.80 | .275 | 1.14 | 6.9 | 3.4 | 4.9 | 68.2 | 52 | 29 | 29 | 3 | 26 | 37 | 3 | 0 | 0 | 0 | 6 | 0 | 2 | 3.63 |
| SP | Koosman, J.Koosman, Jerry >> | 28 | 1970 | L | 73 | 10 | 10 | 4 | 3 | 5.22 | .365 | 1.72 | 11.8 | 3.9 | 4.3 | 58.2 | 76 | 39 | 34 | 6 | 25 | 28 | 2 | 0 | 0 | 0 | 4 | 0 | 1 | 4.67 |
| SP | Lieber, J.Lieber, Jon # >> | 32 | 2002 | R | 61 | 9 | 9 | 4 | 3 | 3.59 | .271 | 1.10 | 8.9 | 1.2 | 6.8 | 62.2 | 61 | 36 | 25 | 7 | 8 | 47 | 1 | 0 | 0 | 0 | 6 | 1 | 0 | 3.39 |
| RP | Schreiber, J.Schreiber, John >> | 28 | 2022 | R | 95 | 22 | 0 | 3 | 2 | 2.14 | .229 | 0.89 | 6.0 | 2.2 | 8.7 | 33.2 | 22 | 8 | 8 | 0 | 8 | 32 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 1.79 |
| RP | Ayrault, B.Ayrault, Bob >> | 26 | 1992 | R | 83 | 22 | 0 | 1 | 2 | 4.85 | .321 | 1.42 | 8.1 | 5.0 | 8.1 | 29.2 | 26 | 17 | 16 | 3 | 16 | 26 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Gleaton, J.Gleaton, Jerry Don >> | 33 | 1990 | L | 86 | 17 | 0 | 0 | 1 | 2.52 | .279 | 1.16 | 7.6 | 2.9 | 5.0 | 25.0 | 21 | 9 | 7 | 2 | 8 | 14 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.88 |
| RP | Brigham, J.Brigham, Jeff >> | 31 | 2023 | R | 84 | 14 | 0 | 2 | 1 | 1.23 | .371 | 1.77 | 7.7 | 9.0 | 5.1 | 14.2 | 12 | 2 | 2 | 2 | 14 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.71 |
| RP | Greene, S.Greene, Shane >> | 28 | 2017 | R | 76 | 8 | 0 | 2 | 0 | 3.72 | .370 | 1.76 | 11.0 | 6.0 | 8.0 | 9.2 | 11 | 4 | 4 | 1 | 6 | 8 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.67 |
| RP | Affeldt, J.Affeldt, Jeremy >> | 28 | 2007 | L | 53 | 10 | 0 | 1 | 1 | 3.86 | .263 | 1.07 | 3.0 | 7.0 | 4.0 | 9.1 | 3 | 4 | 4 | 0 | 7 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.44 |
| SP | Rudolph, D.Rudolph, Dick >> | 32 | 1919 | R | 45 | 3 | 0 | 0 | 0 | 0.00 | .294 | 1.25 | 6.8 | 4.5 | 2.3 | 4.0 | 3 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.00 |