| SP | Mussina, M.Mussina, Mike >> | 27 | 1995 | R | 96 | 26 | 26 | 11 | 9 | 4.08 | .326 | 1.44 | 10.8 | 2.2 | 5.0 | 169.2 | 202 | 100 | 77 | 10 | 42 | 93 | 3 | 0 | 0 | 2 | 16 | 2 | 4 | 3.45 |
| SP | Barker, L.Barker, Len # >> | 27 | 1982 | R | 87 | 25 | 25 | 7 | 12 | 3.84 | .315 | 1.35 | 9.2 | 2.9 | 5.4 | 185.0 | 190 | 96 | 79 | 10 | 59 | 112 | 3 | 0 | 0 | 0 | 13 | 6 | 9 | 3.55 |
| SP | Worley, V.Worley, Vance # >> | 23 | 2011 | R | 85 | 24 | 24 | 5 | 14 | 6.34 | .344 | 1.56 | 10.8 | 3.2 | 5.3 | 122.0 | 147 | 97 | 86 | 16 | 43 | 72 | 0 | 0 | 0 | 0 | 4 | 2 | 5 | 4.63 |
| SP | Shields, J.Shields, James >> | 37 | 2018 | R | 62 | 26 | 23 | 6 | 8 | 5.62 | .322 | 1.39 | 9.5 | 3.2 | 5.2 | 137.2 | 144 | 102 | 86 | 16 | 48 | 79 | 0 | 0 | 0 | 0 | 10 | 4 | 4 | 4.50 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 99 | 68 | 0 | 7 | 6 | 3.05 | .283 | 1.15 | 7.8 | 2.7 | 7.5 | 88.2 | 76 | 32 | 30 | 9 | 26 | 73 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 3.66 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 85 | 60 | 0 | 2 | 0 | 2.62 | .293 | 1.23 | 7.1 | 4.1 | 9.1 | 75.2 | 59 | 24 | 22 | 7 | 34 | 76 | 0 | 7 | 3 | 0 | 0 | 1 | 1 | 3.59 |
| RP | Peralta, W.Peralta, Wandy >> | 25 | 2017 | L | 72 | 57 | 0 | 3 | 6 | 4.18 | .307 | 1.33 | 8.7 | 3.3 | 6.0 | 60.1 | 58 | 31 | 28 | 7 | 22 | 40 | 0 | 4 | 2 | 0 | 0 | 0 | 5 | 4.28 |
| RP | Morales, F.Morales, Franklin >> | 29 | 2015 | L | 66 | 34 | 0 | 1 | 1 | 5.14 | .314 | 1.37 | 7.7 | 4.6 | 5.7 | 35.0 | 30 | 26 | 20 | 3 | 18 | 22 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.40 |
| RP | Bastardo, A.Bastardo, Antonio >> | 29 | 2014 | L | 83 | 26 | 0 | 2 | 0 | 2.57 | .339 | 1.50 | 6.4 | 7.1 | 10.0 | 28.0 | 20 | 9 | 8 | 1 | 22 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.71 |
| RP | Alvarado, J.Alvarado, Jose >> | 29 | 2024 | L | 71 | 29 | 0 | 2 | 0 | 3.68 | .362 | 1.67 | 9.6 | 5.6 | 8.7 | 29.1 | 31 | 14 | 12 | 1 | 18 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 6 | 3.48 |