| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 95 | 12 | 12 | 2 | 7 | 4.93 | .316 | 1.37 | 9.0 | 3.4 | 5.2 | 69.1 | 69 | 40 | 38 | 11 | 26 | 40 | 1 | 0 | 0 | 0 | 5 | 1 | 2 | 5.09 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 11 | 11 | 5 | 3 | 6.16 | .347 | 1.56 | 10.3 | 3.8 | 9.9 | 57.0 | 65 | 45 | 39 | 9 | 24 | 63 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.21 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 11 | 11 | 4 | 5 | 6.30 | .362 | 1.67 | 11.0 | 4.1 | 6.2 | 60.0 | 73 | 42 | 42 | 14 | 27 | 41 | 2 | 0 | 0 | 0 | 3 | 2 | 2 | 6.12 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 12 | 11 | 2 | 7 | 7.33 | .381 | 1.74 | 10.4 | 5.5 | 9.0 | 46.2 | 53 | 40 | 38 | 14 | 28 | 46 | 0 | 0 | 0 | 0 | 3 | 5 | 2 | 7.11 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 90 | 35 | 0 | 1 | 0 | 1.77 | .201 | 0.73 | 4.9 | 1.8 | 9.8 | 35.2 | 19 | 8 | 7 | 1 | 7 | 38 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1.89 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 31 | 0 | 2 | 2 | 4.85 | .316 | 1.36 | 9.9 | 2.3 | 11.8 | 39.0 | 43 | 22 | 21 | 7 | 10 | 51 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.56 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 77 | 21 | 0 | 0 | 2 | 3.46 | .284 | 1.15 | 6.2 | 4.2 | 5.2 | 26.0 | 18 | 11 | 10 | 2 | 12 | 15 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 4.35 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 16 | 0 | 0 | 0 | 2.04 | .321 | 1.36 | 9.5 | 3.2 | 11.6 | 17.2 | 18 | 4 | 4 | 0 | 6 | 22 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 1.65 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 9 | 0 | 0 | 0 | 1.54 | .271 | 1.11 | 5.7 | 4.9 | 10.6 | 11.2 | 7 | 2 | 2 | 1 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.45 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 8 | 0 | 0 | 0 | 2.61 | .279 | 1.06 | 6.3 | 3.6 | 9.9 | 10.1 | 7 | 4 | 3 | 0 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2.30 |