| SP | deGrom, J.deGrom, Jacob † $ >> | 33 | 2021 | R | 100 | 28 | 28 | 12 | 8 | 2.99 | .260 | 1.03 | 6.8 | 2.5 | 9.4 | 192.1 | 145 | 65 | 64 | 23 | 54 | 200 | 1 | 0 | 0 | 0 | 23 | 4 | 0 | 3.38 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 27 | 27 | 9 | 11 | 4.00 | .295 | 1.24 | 8.2 | 3.0 | 7.9 | 177.2 | 161 | 85 | 79 | 30 | 59 | 156 | 0 | 0 | 0 | 0 | 14 | 3 | 3 | 4.49 |
| SP | McDowell, S.McDowell, Sam >> | 28 | 1970 | L | 23 | 25 | 25 | 10 | 10 | 5.39 | .356 | 1.62 | 9.6 | 5.1 | 7.1 | 158.2 | 168 | 96 | 95 | 21 | 89 | 125 | 2 | 0 | 0 | 1 | 13 | 6 | 6 | 4.95 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 81 | 83 | 0 | 7 | 2 | 3.93 | .315 | 1.32 | 7.0 | 4.9 | 8.4 | 73.1 | 57 | 32 | 32 | 8 | 40 | 68 | 0 | 0 | 3 | 0 | 0 | 4 | 0 | 4.37 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 92 | 45 | 0 | 1 | 3 | 4.24 | .310 | 1.33 | 9.0 | 3.1 | 11.2 | 46.2 | 46 | 22 | 22 | 7 | 16 | 57 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 3.61 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 64 | 0 | 5 | 4 | 2.48 | .255 | 1.01 | 5.3 | 3.9 | 12.2 | 65.1 | 38 | 19 | 18 | 4 | 28 | 88 | 0 | 35 | 3 | 0 | 0 | 1 | 0 | 2.43 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 10 | 0 | 3 | 1 | 3.21 | .344 | 1.57 | 10.3 | 3.9 | 3.9 | 14.0 | 16 | 5 | 5 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.36 |