| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 12 | 12 | 6 | 4 | 3.38 | .284 | 1.18 | 7.2 | 3.4 | 10.2 | 77.1 | 62 | 30 | 29 | 5 | 29 | 87 | 1 | 0 | 0 | 0 | 8 | 1 | 2 | 2.75 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 12 | 12 | 4 | 4 | 4.36 | .295 | 1.26 | 7.8 | 3.5 | 9.8 | 66.0 | 57 | 32 | 32 | 11 | 26 | 72 | 1 | 0 | 0 | 1 | 6 | 0 | 4 | 4.17 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 77 | 11 | 11 | 2 | 5 | 5.63 | .353 | 1.62 | 11.8 | 2.8 | 9.0 | 54.1 | 71 | 35 | 34 | 14 | 17 | 54 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 5.37 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 67 | 10 | 10 | 5 | 3 | 6.02 | .325 | 1.45 | 10.6 | 2.5 | 8.3 | 55.1 | 65 | 38 | 37 | 7 | 15 | 51 | 1 | 0 | 0 | 0 | 3 | 0 | 2 | 3.62 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 27 | 0 | 3 | 0 | 2.51 | .302 | 1.27 | 9.0 | 2.5 | 13.2 | 32.1 | 32 | 9 | 9 | 5 | 9 | 47 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.03 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 26 | 0 | 2 | 0 | 6.03 | .299 | 1.28 | 8.4 | 3.2 | 9.9 | 31.1 | 29 | 21 | 21 | 9 | 11 | 34 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.65 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 17 | 0 | 2 | 0 | 0.00 | .120 | 0.41 | 3.3 | 0.4 | 11.0 | 22.0 | 8 | 0 | 0 | 0 | 1 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0.68 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 11 | 0 | 0 | 2 | 6.28 | .358 | 1.67 | 10.3 | 5.1 | 6.4 | 14.1 | 16 | 10 | 10 | 3 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.07 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 63 | 17 | 0 | 2 | 0 | 3.60 | .308 | 1.27 | 9.6 | 1.8 | 7.8 | 15.0 | 16 | 6 | 6 | 1 | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.93 |
| SU | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 17 | 0 | 0 | 1 | 2.45 | .295 | 1.20 | 6.5 | 4.5 | 9.5 | 18.1 | 13 | 5 | 5 | 1 | 9 | 19 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.28 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 17 | 0 | 1 | 0 | 0.00 | .192 | 0.67 | 3.9 | 2.1 | 9.0 | 21.0 | 9 | 0 | 0 | 0 | 5 | 21 | 0 | 12 | 0 | 0 | 0 | 1 | 0 | 1.86 |