| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 12 | 12 | 6 | 5 | 3.01 | .262 | 1.05 | 7.6 | 2.0 | 10.3 | 83.2 | 70 | 30 | 28 | 13 | 18 | 95 | 0 | 0 | 0 | 0 | 9 | 1 | 0 | 3.43 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 12 | 12 | 3 | 6 | 4.10 | .294 | 1.20 | 8.0 | 2.8 | 7.9 | 83.1 | 74 | 40 | 38 | 9 | 26 | 73 | 1 | 0 | 0 | 0 | 7 | 4 | 2 | 3.73 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 12 | 12 | 6 | 2 | 3.24 | .254 | 1.01 | 5.5 | 3.7 | 6.4 | 66.2 | 40 | 25 | 24 | 3 | 27 | 47 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 3.44 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 85 | 11 | 11 | 6 | 3 | 4.30 | .295 | 1.23 | 8.3 | 2.8 | 5.7 | 73.1 | 67 | 36 | 35 | 9 | 23 | 46 | 1 | 0 | 0 | 1 | 6 | 2 | 2 | 4.37 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 11 | 11 | 3 | 2 | 3.04 | .291 | 1.21 | 8.5 | 2.5 | 9.7 | 50.1 | 47 | 17 | 17 | 4 | 14 | 54 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 2.78 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 31 | 0 | 4 | 0 | 1.42 | .230 | 0.89 | 3.3 | 4.7 | 7.8 | 38.0 | 14 | 6 | 6 | 1 | 20 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.18 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 15 | 0 | 0 | 3 | 3.52 | .281 | 1.17 | 6.6 | 4.2 | 10.8 | 15.1 | 11 | 7 | 6 | 2 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 14 | 0 | 2 | 0 | 3.78 | .286 | 1.20 | 5.6 | 5.6 | 8.4 | 16.2 | 10 | 7 | 7 | 1 | 10 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 9 | 0 | 0 | 0 | 2.70 | .302 | 1.20 | 6.3 | 4.5 | 3.6 | 10.0 | 7 | 3 | 3 | 0 | 5 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.00 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 11 | 0 | 2 | 2 | 2.76 | .332 | 1.45 | 9.0 | 4.2 | 6.6 | 45.2 | 45 | 19 | 14 | 9 | 21 | 33 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.67 |