| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 98 | 36 | 36 | 14 | 19 | 3.74 | .300 | 1.26 | 9.1 | 2.2 | 9.6 | 269.1 | 272 | 115 | 112 | 38 | 67 | 288 | 7 | 0 | 0 | 2 | 20 | 7 | 5 | 3.52 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 79 | 35 | 35 | 15 | 8 | 3.56 | .310 | 1.34 | 8.4 | 3.6 | 10.2 | 240.1 | 224 | 101 | 95 | 27 | 97 | 271 | 1 | 0 | 0 | 1 | 24 | 3 | 4 | 3.45 |
| SP | Shields, J.Shields, James # >> | 30 | 2011 | R | 62 | 33 | 33 | 14 | 12 | 5.45 | .335 | 1.49 | 9.7 | 3.7 | 8.4 | 231.0 | 250 | 146 | 140 | 42 | 94 | 216 | 5 | 0 | 0 | 1 | 13 | 5 | 6 | 4.78 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 46 | 32 | 31 | 11 | 11 | 5.40 | .357 | 1.66 | 10.0 | 5.0 | 10.1 | 183.1 | 203 | 110 | 110 | 26 | 101 | 206 | 0 | 0 | 0 | 0 | 12 | 2 | 6 | 4.28 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 97 | 0 | 6 | 9 | 3.36 | .283 | 1.15 | 7.4 | 3.0 | 11.0 | 118.0 | 97 | 46 | 44 | 15 | 39 | 144 | 0 | 20 | 7 | 0 | 0 | 4 | 3 | 3.31 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 78 | 81 | 0 | 4 | 1 | 3.77 | .308 | 1.33 | 8.4 | 3.7 | 7.6 | 90.2 | 84 | 39 | 38 | 11 | 37 | 76 | 0 | 15 | 2 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 61 | 54 | 0 | 7 | 2 | 4.04 | .353 | 1.58 | 7.7 | 6.7 | 7.9 | 55.2 | 47 | 27 | 25 | 8 | 41 | 48 | 0 | 6 | 5 | 0 | 0 | 3 | 2 | 5.55 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 34 | 2014 | R | 45 | 45 | 0 | 2 | 5 | 3.81 | .297 | 1.25 | 8.3 | 2.9 | 5.7 | 52.0 | 48 | 22 | 22 | 6 | 17 | 33 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.27 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 35 | 36 | 0 | 2 | 2 | 2.92 | .323 | 1.38 | 7.5 | 4.9 | 10.2 | 37.0 | 31 | 12 | 12 | 2 | 20 | 42 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 3.22 |