| SP | Tiant, L.Tiant, Luis $ >> | 28 | 1968 | R | 97 | 29 | 29 | 11 | 15 | 4.12 | .300 | 1.26 | 7.7 | 3.7 | 7.9 | 211.2 | 180 | 107 | 97 | 19 | 87 | 185 | 8 | 0 | 0 | 1 | 14 | 5 | 4 | 3.73 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 28 | 28 | 8 | 15 | 4.33 | .289 | 1.20 | 8.9 | 1.9 | 5.4 | 206.0 | 204 | 106 | 99 | 19 | 44 | 124 | 10 | 0 | 0 | 2 | 15 | 3 | 3 | 3.68 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 25 | 25 | 9 | 12 | 4.85 | .324 | 1.44 | 10.0 | 2.9 | 4.2 | 163.1 | 182 | 92 | 88 | 20 | 53 | 76 | 2 | 0 | 0 | 1 | 9 | 0 | 2 | 4.64 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 72 | 0 | 3 | 3 | 3.55 | .267 | 1.09 | 6.6 | 3.3 | 8.1 | 91.1 | 67 | 38 | 36 | 13 | 33 | 82 | 0 | 10 | 2 | 0 | 0 | 0 | 2 | 4.14 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 52 | 0 | 1 | 3 | 2.53 | .297 | 1.25 | 7.5 | 3.8 | 9.4 | 64.0 | 53 | 20 | 18 | 6 | 27 | 67 | 0 | 5 | 2 | 0 | 0 | 1 | 3 | 3.44 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 41 | 0 | 2 | 4 | 3.86 | .287 | 1.21 | 7.8 | 3.2 | 9.0 | 51.1 | 44 | 25 | 22 | 8 | 18 | 51 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 4.10 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 41 | 0 | 2 | 2 | 5.88 | .340 | 1.55 | 10.5 | 3.5 | 9.7 | 41.1 | 48 | 27 | 27 | 8 | 16 | 44 | 0 | 1 | 4 | 0 | 0 | 0 | 2 | 4.56 |