| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 28 | 28 | 15 | 7 | 2.79 | .245 | 0.96 | 6.9 | 1.7 | 8.2 | 232.0 | 178 | 77 | 72 | 27 | 45 | 212 | 14 | 0 | 0 | 5 | 17 | 3 | 1 | 3.31 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 28 | 28 | 5 | 11 | 3.88 | .299 | 1.27 | 7.8 | 3.6 | 7.6 | 192.1 | 167 | 90 | 83 | 20 | 77 | 163 | 1 | 0 | 0 | 0 | 17 | 2 | 2 | 3.89 |
| SP | Kluber, C.Kluber, Corey † # >> | 31 | 2017 | R | 90 | 27 | 27 | 15 | 6 | 3.29 | .258 | 1.01 | 7.5 | 1.6 | 8.6 | 205.0 | 171 | 81 | 75 | 27 | 36 | 196 | 8 | 0 | 0 | 3 | 17 | 7 | 1 | 3.43 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 28 | 27 | 11 | 9 | 4.48 | .294 | 1.24 | 8.3 | 2.8 | 8.4 | 191.0 | 177 | 98 | 95 | 30 | 59 | 178 | 5 | 0 | 0 | 0 | 15 | 3 | 3 | 4.15 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 27 | 27 | 12 | 14 | 4.36 | .284 | 1.17 | 8.5 | 2.1 | 4.7 | 206.1 | 194 | 107 | 100 | 27 | 48 | 107 | 15 | 0 | 0 | 1 | 10 | 4 | 3 | 4.42 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 71 | 0 | 6 | 3 | 1.73 | .241 | 0.95 | 5.6 | 3.0 | 11.3 | 88.1 | 55 | 17 | 17 | 8 | 29 | 110 | 0 | 11 | 4 | 0 | 0 | 0 | 10 | 2.67 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 46 | 0 | 10 | 4 | 3.71 | .269 | 1.11 | 8.0 | 2.0 | 8.7 | 53.1 | 47 | 23 | 22 | 10 | 12 | 51 | 0 | 6 | 6 | 0 | 0 | 0 | 2 | 4.21 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 31 | 0 | 2 | 5 | 3.60 | .318 | 1.40 | 8.7 | 3.9 | 7.2 | 30.0 | 29 | 12 | 12 | 5 | 13 | 24 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.87 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 14 | 0 | 1 | 1 | 4.50 | .326 | 1.45 | 10.4 | 2.7 | 5.0 | 20.0 | 23 | 10 | 10 | 3 | 6 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.75 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 14 | 0 | 0 | 0 | 4.24 | .320 | 1.29 | 5.3 | 6.4 | 9.0 | 17.0 | 10 | 8 | 8 | 3 | 12 | 17 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.76 |