| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 14 | 14 | 4 | 5 | 3.67 | .313 | 1.37 | 9.0 | 3.4 | 7.8 | 83.1 | 83 | 34 | 34 | 10 | 31 | 72 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 3.95 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 14 | 14 | 7 | 5 | 4.65 | .317 | 1.39 | 10.0 | 2.6 | 8.7 | 81.1 | 90 | 47 | 42 | 10 | 23 | 78 | 2 | 0 | 0 | 0 | 8 | 0 | 3 | 3.53 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 14 | 14 | 7 | 2 | 4.07 | .308 | 1.31 | 7.9 | 4.0 | 5.7 | 90.2 | 79 | 41 | 41 | 11 | 40 | 57 | 3 | 0 | 0 | 1 | 8 | 2 | 0 | 4.72 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 13 | 13 | 5 | 1 | 4.15 | .318 | 1.37 | 9.7 | 2.7 | 5.8 | 86.2 | 93 | 46 | 40 | 10 | 26 | 55 | 2 | 0 | 0 | 0 | 6 | 2 | 1 | 4.21 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 28 | 0 | 6 | 2 | 2.27 | .240 | 0.95 | 6.1 | 2.6 | 7.3 | 31.2 | 21 | 8 | 8 | 4 | 9 | 25 | 0 | 12 | 1 | 0 | 0 | 0 | 0 | 3.94 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 23 | 0 | 0 | 1 | 4.03 | .287 | 1.21 | 6.8 | 4.0 | 7.4 | 29.0 | 22 | 13 | 13 | 4 | 13 | 24 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 4.48 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 20 | 0 | 2 | 1 | 10.20 | .438 | 2.33 | 13.8 | 7.2 | 7.2 | 15.0 | 23 | 18 | 17 | 3 | 12 | 12 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6.40 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 41 | 0 | 2 | 3 | 2.01 | .210 | 0.80 | 4.4 | 2.9 | 7.3 | 31.1 | 15 | 7 | 7 | 2 | 10 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.19 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 16 | 0 | 4 | 0 | 3.54 | .307 | 1.28 | 7.4 | 4.3 | 5.2 | 40.2 | 33 | 17 | 16 | 6 | 19 | 23 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 5.38 |