| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 33 | 33 | 12 | 14 | 4.15 | .283 | 1.17 | 8.6 | 1.9 | 4.8 | 245.1 | 234 | 116 | 113 | 37 | 52 | 130 | 12 | 0 | 0 | 2 | 16 | 5 | 4 | 4.60 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 31 | 31 | 9 | 17 | 5.99 | .347 | 1.58 | 11.2 | 3.0 | 5.0 | 200.0 | 249 | 137 | 133 | 32 | 66 | 111 | 8 | 0 | 0 | 0 | 10 | 4 | 4 | 5.02 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 33 | 30 | 6 | 14 | 5.95 | .347 | 1.57 | 10.3 | 3.8 | 5.1 | 174.0 | 200 | 122 | 115 | 28 | 73 | 99 | 1 | 1 | 0 | 0 | 13 | 4 | 3 | 5.28 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 88 | 0 | 6 | 3 | 3.48 | .286 | 1.17 | 8.1 | 2.4 | 7.9 | 132.0 | 119 | 56 | 51 | 14 | 35 | 116 | 0 | 7 | 4 | 0 | 0 | 5 | 4 | 3.53 |
| RP | Clippard, T.Clippard, Tyler # >> | 26 | 2011 | R | 79 | 81 | 0 | 4 | 8 | 3.42 | .278 | 1.12 | 6.9 | 3.3 | 8.6 | 110.2 | 84 | 47 | 42 | 7 | 40 | 105 | 0 | 7 | 3 | 0 | 0 | 4 | 0 | 3.12 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 70 | 0 | 4 | 7 | 5.91 | .386 | 1.86 | 10.1 | 6.8 | 7.5 | 74.2 | 83 | 56 | 49 | 16 | 56 | 62 | 0 | 3 | 4 | 0 | 0 | 2 | 4 | 6.49 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 51 | 0 | 2 | 3 | 4.62 | .307 | 1.32 | 8.3 | 3.6 | 8.1 | 62.1 | 57 | 33 | 32 | 4 | 25 | 56 | 0 | 5 | 3 | 0 | 0 | 1 | 4 | 3.29 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 55 | 29 | 1 | 3 | 7 | 6.93 | .367 | 1.70 | 10.5 | 4.9 | 4.7 | 61.0 | 71 | 47 | 47 | 8 | 33 | 32 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 5.38 |