| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 13 | 12 | 4.57 | .307 | 1.32 | 9.3 | 2.5 | 7.6 | 212.2 | 220 | 116 | 108 | 32 | 60 | 180 | 1 | 0 | 0 | 1 | 16 | 2 | 5 | 4.14 |
| SP | Brown, M.Brown, Mordecai † # >> | 32 | 1908 | R | 84 | 33 | 33 | 18 | 9 | 3.61 | .285 | 1.17 | 8.4 | 2.2 | 4.2 | 254.0 | 236 | 106 | 102 | 30 | 62 | 119 | 11 | 0 | 0 | 2 | 20 | 5 | 3 | 4.39 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 32 | 32 | 12 | 11 | 4.29 | .321 | 1.40 | 9.0 | 3.6 | 4.4 | 210.0 | 211 | 113 | 100 | 18 | 83 | 103 | 4 | 0 | 0 | 1 | 20 | 4 | 4 | 4.38 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 32 | 32 | 9 | 12 | 5.54 | .348 | 1.58 | 10.3 | 4.0 | 3.6 | 188.1 | 215 | 125 | 116 | 25 | 83 | 76 | 0 | 0 | 0 | 0 | 15 | 4 | 6 | 5.31 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 32 | 31 | 5 | 16 | 5.74 | .367 | 1.70 | 9.8 | 5.5 | 9.3 | 163.0 | 177 | 106 | 104 | 20 | 100 | 168 | 0 | 0 | 0 | 0 | 11 | 6 | 3 | 4.48 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 84 | 0 | 5 | 8 | 3.23 | .303 | 1.26 | 6.8 | 4.6 | 8.7 | 133.2 | 101 | 52 | 48 | 7 | 68 | 129 | 0 | 11 | 2 | 0 | 0 | 5 | 0 | 3.39 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 71 | 0 | 3 | 6 | 3.66 | .288 | 1.16 | 8.4 | 2.0 | 7.7 | 93.1 | 87 | 38 | 38 | 11 | 21 | 80 | 0 | 4 | 2 | 0 | 0 | 5 | 1 | 3.66 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 47 | 0 | 4 | 4 | 3.49 | .326 | 1.42 | 8.8 | 4.0 | 6.3 | 59.1 | 58 | 28 | 23 | 7 | 26 | 41 | 0 | 7 | 3 | 0 | 0 | 2 | 0 | 4.58 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 37 | 0 | 1 | 2 | 4.78 | .344 | 1.54 | 11.3 | 2.8 | 5.7 | 52.2 | 65 | 28 | 28 | 4 | 16 | 33 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 3.77 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 18 | 0 | 1 | 4 | 6.68 | .363 | 1.71 | 12.8 | 2.6 | 9.6 | 31.0 | 44 | 23 | 23 | 9 | 9 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.52 |