| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 13 | 13 | 6 | 4 | 3.08 | .291 | 1.21 | 8.9 | 2.1 | 8.0 | 87.2 | 86 | 35 | 30 | 9 | 20 | 77 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 3.33 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 13 | 13 | 7 | 6 | 4.65 | .297 | 1.25 | 9.4 | 1.9 | 4.8 | 98.2 | 102 | 52 | 51 | 14 | 21 | 52 | 5 | 0 | 0 | 1 | 6 | 2 | 2 | 4.50 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 74 | 12 | 12 | 6 | 3 | 4.31 | .294 | 1.20 | 8.0 | 2.8 | 7.5 | 79.1 | 70 | 43 | 38 | 9 | 25 | 66 | 3 | 0 | 0 | 1 | 7 | 4 | 2 | 3.91 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 12 | 12 | 5 | 6 | 5.50 | .341 | 1.54 | 10.4 | 3.5 | 3.6 | 90.0 | 104 | 56 | 55 | 12 | 35 | 36 | 5 | 0 | 0 | 1 | 4 | 1 | 1 | 5.13 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 33 | 0 | 2 | 1 | 3.32 | .278 | 1.13 | 8.2 | 2.1 | 8.8 | 43.1 | 39 | 16 | 16 | 6 | 10 | 42 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 15 | 0 | 0 | 1 | 7.90 | .438 | 2.20 | 13.8 | 6.9 | 6.9 | 13.2 | 20 | 13 | 12 | 4 | 10 | 10 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 8.23 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 10 | 0 | 0 | 0 | 4.63 | .314 | 1.37 | 10.6 | 2.5 | 10.6 | 11.2 | 13 | 6 | 6 | 3 | 3 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 14 | 0 | 1 | 1 | 2.70 | .259 | 1.05 | 5.9 | 3.6 | 7.2 | 20.0 | 13 | 6 | 6 | 1 | 8 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.25 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 6 | 0 | 0 | 1 | 15.58 | .509 | 3.00 | 23.6 | 5.6 | 5.6 | 8.2 | 21 | 17 | 15 | 4 | 5 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 10.50 |