| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 20 | 20 | 9 | 6 | 3.21 | .297 | 1.24 | 7.5 | 3.6 | 8.8 | 146.0 | 122 | 65 | 52 | 15 | 59 | 142 | 3 | 0 | 0 | 1 | 13 | 4 | 2 | 3.68 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 19 | 19 | 4 | 7 | 4.47 | .330 | 1.46 | 7.6 | 5.6 | 8.1 | 118.2 | 99 | 71 | 59 | 14 | 74 | 106 | 0 | 0 | 0 | 0 | 12 | 2 | 3 | 4.68 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 18 | 18 | 6 | 8 | 4.31 | .297 | 1.24 | 9.6 | 1.6 | 6.0 | 121.0 | 129 | 63 | 58 | 13 | 21 | 81 | 2 | 0 | 0 | 1 | 10 | 3 | 3 | 3.65 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 46 | 17 | 17 | 6 | 5 | 5.43 | .345 | 1.56 | 9.3 | 4.8 | 8.7 | 104.1 | 107 | 69 | 63 | 14 | 56 | 101 | 0 | 0 | 0 | 0 | 7 | 2 | 4 | 4.48 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 31 | 0 | 0 | 4 | 7.03 | .397 | 1.89 | 10.5 | 6.8 | 7.9 | 24.1 | 28 | 19 | 19 | 6 | 18 | 21 | 0 | 16 | 5 | 0 | 0 | 2 | 2 | 7.00 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 46 | 0 | 4 | 7 | 6.47 | .376 | 1.75 | 11.3 | 4.7 | 9.0 | 48.2 | 60 | 42 | 35 | 7 | 25 | 48 | 0 | 1 | 4 | 0 | 0 | 3 | 1 | 4.65 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 32 | 0 | 1 | 1 | 4.03 | .345 | 1.58 | 9.0 | 5.2 | 8.3 | 38.0 | 38 | 21 | 17 | 1 | 22 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.24 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 28 | 0 | 0 | 2 | 3.38 | .313 | 1.33 | 8.1 | 4.0 | 8.4 | 29.1 | 26 | 11 | 11 | 4 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.38 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 28 | 0 | 2 | 0 | 1.32 | .271 | 1.12 | 7.1 | 2.9 | 9.5 | 34.0 | 27 | 6 | 5 | 2 | 11 | 36 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.62 |