| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 34 | 33 | 17 | 7 | 3.09 | .285 | 1.17 | 6.4 | 4.1 | 4.5 | 218.1 | 156 | 77 | 75 | 11 | 100 | 109 | 0 | 0 | 0 | 0 | 23 | 5 | 1 | 4.10 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 86 | 32 | 32 | 17 | 9 | 3.42 | .291 | 1.20 | 9.0 | 1.9 | 4.6 | 210.2 | 209 | 85 | 80 | 18 | 44 | 107 | 1 | 0 | 0 | 1 | 22 | 6 | 2 | 3.81 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 32 | 32 | 13 | 10 | 3.83 | .327 | 1.44 | 8.9 | 4.1 | 7.1 | 190.1 | 188 | 84 | 81 | 24 | 86 | 150 | 3 | 0 | 0 | 1 | 14 | 4 | 0 | 4.48 |
| CL | Chapman, A.Chapman, Aroldis # >> | 26 | 2014 | L | 94 | 87 | 0 | 4 | 5 | 2.61 | .277 | 1.12 | 5.6 | 4.5 | 10.3 | 107.0 | 67 | 31 | 31 | 4 | 53 | 123 | 0 | 8 | 1 | 0 | 0 | 3 | 6 | 2.76 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 68 | 0 | 4 | 3 | 3.01 | .257 | 1.04 | 6.3 | 3.1 | 8.7 | 86.2 | 60 | 29 | 29 | 11 | 30 | 83 | 0 | 12 | 2 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 52 | 0 | 2 | 4 | 1.96 | .238 | 0.92 | 4.7 | 3.7 | 8.4 | 59.2 | 31 | 14 | 13 | 6 | 24 | 55 | 0 | 12 | 2 | 0 | 0 | 1 | 2 | 3.73 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 31 | 0 | 1 | 2 | 4.65 | .285 | 1.13 | 7.5 | 2.6 | 7.5 | 31.0 | 26 | 16 | 16 | 7 | 9 | 26 | 0 | 3 | 1 | 0 | 0 | 2 | 6 | 5.32 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 11 | 0 | 2 | 1 | 3.21 | .288 | 1.21 | 8.4 | 2.6 | 7.7 | 14.0 | 13 | 5 | 5 | 2 | 4 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 26 | 0 | 4 | 2 | 3.32 | .298 | 1.26 | 7.8 | 3.7 | 6.4 | 59.2 | 51 | 22 | 22 | 5 | 24 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.95 |