| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 23 | 23 | 12 | 10 | 3.92 | .297 | 1.23 | 8.1 | 3.0 | 8.6 | 163.0 | 146 | 78 | 71 | 14 | 55 | 155 | 2 | 0 | 0 | 1 | 14 | 6 | 5 | 3.34 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 22 | 22 | 8 | 8 | 3.52 | .272 | 1.12 | 7.5 | 2.6 | 5.0 | 127.2 | 106 | 53 | 50 | 16 | 37 | 70 | 0 | 0 | 0 | 0 | 11 | 0 | 0 | 4.41 |
| SP | Valenzuela, F.Valenzuela, Fernando # >> | 21 | 1981 | L | 60 | 22 | 22 | 7 | 5 | 3.73 | .311 | 1.32 | 8.2 | 3.7 | 7.2 | 157.0 | 143 | 69 | 65 | 21 | 65 | 126 | 2 | 0 | 0 | 0 | 15 | 5 | 4 | 4.47 |
| RP | Edwards, C.Edwards, Carl † >> | 24 | 2016 | R | 92 | 62 | 0 | 3 | 3 | 2.97 | .275 | 1.12 | 5.9 | 4.3 | 9.7 | 75.2 | 49 | 25 | 25 | 10 | 36 | 81 | 0 | 7 | 2 | 0 | 0 | 1 | 4 | 4.05 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 61 | 48 | 0 | 4 | 4 | 4.89 | .319 | 1.35 | 7.6 | 4.6 | 10.2 | 53.1 | 45 | 29 | 29 | 9 | 27 | 60 | 0 | 8 | 1 | 0 | 0 | 3 | 3 | 4.64 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 54 | 37 | 0 | 5 | 2 | 3.32 | .244 | 0.92 | 6.3 | 2.1 | 10.5 | 43.1 | 30 | 16 | 16 | 5 | 10 | 50 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 3.02 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 46 | 33 | 0 | 2 | 0 | 2.13 | .255 | 1.03 | 6.6 | 2.6 | 10.2 | 38.0 | 28 | 9 | 9 | 4 | 11 | 43 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.97 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Messersmith, A.Messersmith, Andy >> | 30 | 1975 | R | 40 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Candelaria, J.Candelaria, John >> | 33 | 1986 | L | 54 | 13 | 0 | 2 | 0 | 5.59 | .320 | 1.41 | 9.3 | 3.4 | 7.8 | 29.0 | 30 | 18 | 18 | 3 | 11 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.76 |