| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 19 | 19 | 8 | 2 | 2.08 | .261 | 1.04 | 6.2 | 3.1 | 10.0 | 130.0 | 90 | 30 | 30 | 13 | 45 | 145 | 1 | 0 | 0 | 0 | 16 | 3 | 0 | 3.18 |
| SP | Johnson, R.Johnson, Randy † $$ >> | 41 | 2004 | L | 89 | 19 | 18 | 14 | 2 | 2.69 | .266 | 1.06 | 7.6 | 2.0 | 8.5 | 137.1 | 115 | 43 | 41 | 16 | 30 | 130 | 5 | 1 | 0 | 0 | 13 | 4 | 0 | 3.36 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 18 | 18 | 5 | 10 | 5.34 | .342 | 1.53 | 10.3 | 3.6 | 5.3 | 114.2 | 131 | 71 | 68 | 17 | 45 | 67 | 2 | 0 | 0 | 1 | 8 | 3 | 1 | 5.03 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 77 | 18 | 18 | 5 | 8 | 6.46 | .343 | 1.56 | 10.6 | 3.6 | 7.0 | 108.2 | 127 | 78 | 78 | 24 | 43 | 84 | 2 | 0 | 0 | 0 | 5 | 0 | 5 | 5.53 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 17 | 17 | 5 | 9 | 6.20 | .367 | 1.66 | 11.2 | 3.8 | 6.4 | 97.1 | 121 | 73 | 67 | 10 | 41 | 69 | 1 | 0 | 0 | 0 | 6 | 7 | 4 | 4.40 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 38 | 0 | 1 | 6 | 4.54 | .252 | 1.01 | 7.8 | 1.5 | 12.6 | 37.2 | 32 | 21 | 19 | 10 | 6 | 52 | 0 | 22 | 3 | 0 | 0 | 0 | 1 | 4.19 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 32 | 0 | 1 | 4 | 5.12 | .326 | 1.45 | 8.4 | 4.9 | 6.7 | 31.2 | 29 | 18 | 18 | 8 | 17 | 23 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 6.52 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 29 | 0 | 4 | 1 | 4.10 | .325 | 1.44 | 8.0 | 5.2 | 8.0 | 26.1 | 23 | 13 | 12 | 3 | 15 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.46 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 18 | 0 | 0 | 0 | 6.50 | .379 | 1.78 | 11.5 | 4.5 | 8.0 | 18.0 | 23 | 13 | 13 | 2 | 9 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.33 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 13 | 0 | 1 | 1 | 5.14 | .320 | 1.41 | 8.7 | 4.0 | 6.1 | 63.0 | 61 | 37 | 36 | 10 | 28 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.03 |