| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 23 | 23 | 7 | 11 | 5.10 | .324 | 1.42 | 9.5 | 3.3 | 10.3 | 144.2 | 152 | 87 | 82 | 28 | 53 | 165 | 3 | 0 | 0 | 1 | 9 | 3 | 3 | 4.40 |
| SP | McClanahan, S.McClanahan, Shane # >> | 25 | 2022 | L | 89 | 22 | 22 | 8 | 7 | 5.60 | .326 | 1.45 | 9.4 | 3.7 | 9.8 | 128.2 | 133 | 84 | 80 | 22 | 53 | 139 | 0 | 0 | 0 | 0 | 9 | 1 | 5 | 4.33 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 83 | 22 | 22 | 8 | 7 | 4.60 | .328 | 1.45 | 9.3 | 3.8 | 9.3 | 131.0 | 135 | 71 | 67 | 22 | 55 | 136 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 4.41 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 74 | 22 | 22 | 2 | 10 | 7.16 | .397 | 1.96 | 12.7 | 5.0 | 9.3 | 83.0 | 117 | 70 | 66 | 16 | 46 | 86 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.13 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 28 | 2017 | R | 66 | 24 | 22 | 11 | 7 | 5.24 | .335 | 1.50 | 9.7 | 3.9 | 8.2 | 137.1 | 147 | 80 | 80 | 22 | 59 | 125 | 2 | 0 | 0 | 1 | 8 | 2 | 0 | 4.60 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 68 | 0 | 0 | 1 | 2.32 | .233 | 0.91 | 5.7 | 2.6 | 9.8 | 81.1 | 51 | 24 | 21 | 5 | 23 | 88 | 0 | 4 | 3 | 0 | 0 | 0 | 2 | 2.48 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 85 | 68 | 0 | 4 | 0 | 3.38 | .287 | 1.21 | 7.1 | 3.9 | 13.0 | 58.2 | 46 | 25 | 22 | 7 | 25 | 84 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.97 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 72 | 56 | 0 | 1 | 6 | 2.11 | .270 | 1.06 | 6.2 | 3.4 | 10.1 | 64.0 | 44 | 17 | 15 | 5 | 24 | 72 | 0 | 6 | 4 | 0 | 0 | 3 | 1 | 3.03 |