| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 32 | 32 | 15 | 13 | 4.15 | .289 | 1.19 | 8.5 | 2.3 | 7.2 | 227.2 | 214 | 112 | 105 | 41 | 58 | 181 | 5 | 0 | 0 | 1 | 17 | 6 | 1 | 4.60 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 29 | 29 | 8 | 13 | 5.36 | .341 | 1.55 | 10.3 | 3.6 | 6.4 | 181.1 | 208 | 109 | 108 | 40 | 73 | 128 | 2 | 0 | 0 | 1 | 12 | 0 | 3 | 5.67 |
| SP | Wilson, D.Wilson, Don # >> | 26 | 1971 | R | 59 | 31 | 31 | 13 | 8 | 4.75 | .294 | 1.24 | 8.4 | 2.7 | 6.5 | 206.1 | 193 | 114 | 109 | 31 | 62 | 148 | 3 | 0 | 0 | 1 | 15 | 3 | 2 | 4.47 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 59 | 30 | 30 | 15 | 13 | 4.81 | .325 | 1.41 | 8.7 | 4.0 | 8.6 | 198.1 | 191 | 112 | 106 | 30 | 89 | 190 | 5 | 0 | 0 | 2 | 13 | 7 | 11 | 4.51 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 57 | 28 | 28 | 9 | 7 | 5.78 | .341 | 1.52 | 10.5 | 3.2 | 6.1 | 176.0 | 205 | 117 | 113 | 26 | 63 | 119 | 5 | 0 | 0 | 2 | 9 | 5 | 2 | 4.73 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 81 | 0 | 5 | 5 | 4.09 | .286 | 1.18 | 6.9 | 3.8 | 10.4 | 103.1 | 79 | 47 | 47 | 14 | 43 | 119 | 0 | 9 | 3 | 0 | 0 | 2 | 10 | 3.77 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 66 | 0 | 3 | 6 | 4.52 | .323 | 1.40 | 7.1 | 5.6 | 8.9 | 81.2 | 64 | 41 | 41 | 11 | 50 | 80 | 0 | 11 | 2 | 0 | 0 | 3 | 3 | 4.75 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 54 | 54 | 0 | 4 | 3 | 7.06 | .344 | 1.52 | 11.1 | 2.7 | 10.3 | 57.1 | 70 | 46 | 45 | 16 | 17 | 65 | 0 | 2 | 7 | 0 | 0 | 3 | 4 | 5.42 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 54 | 2 | 2 | 0 | 2 | 8.44 | .396 | 1.97 | 13.5 | 5.4 | 7.2 | 10.2 | 15 | 10 | 10 | 6 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.00 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 50 | 6 | 1 | 0 | 2 | 6.30 | .434 | 2.30 | 11.7 | 9.0 | 7.2 | 10.0 | 13 | 12 | 7 | 4 | 10 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.60 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 41 | 30 | 0 | 4 | 1 | 4.48 | .325 | 1.41 | 9.2 | 3.6 | 10.7 | 60.1 | 61 | 30 | 30 | 8 | 24 | 71 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 3.67 |