| SP | Kershaw, C.Kershaw, Clayton † $ >> | 28 | 2016 | L | 98 | 25 | 25 | 16 | 6 | 2.80 | .241 | 0.94 | 7.4 | 1.1 | 9.2 | 199.0 | 163 | 62 | 62 | 16 | 25 | 204 | 11 | 0 | 0 | 2 | 18 | 2 | 2 | 2.40 |
| SP | Santana, J.Santana, Johan # $ >> | 25 | 2004 | L | 91 | 24 | 24 | 11 | 7 | 3.47 | .261 | 1.04 | 7.3 | 2.0 | 9.2 | 173.2 | 141 | 68 | 67 | 23 | 39 | 176 | 4 | 0 | 0 | 1 | 15 | 4 | 4 | 3.44 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 23 | 23 | 16 | 4 | 2.94 | .279 | 1.14 | 7.6 | 2.7 | 6.2 | 177.2 | 150 | 59 | 58 | 15 | 53 | 121 | 8 | 0 | 0 | 1 | 15 | 3 | 4 | 3.68 |
| SP | Fernandez, S.Fernandez, Sid $ >> | 23 | 1985 | L | 53 | 23 | 23 | 13 | 6 | 3.02 | .264 | 1.06 | 5.4 | 4.2 | 8.3 | 160.2 | 96 | 57 | 54 | 18 | 75 | 148 | 2 | 0 | 0 | 1 | 17 | 2 | 0 | 4.06 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 81 | 23 | 23 | 8 | 11 | 4.63 | .317 | 1.38 | 9.1 | 3.4 | 6.7 | 159.1 | 160 | 88 | 82 | 27 | 60 | 118 | 7 | 0 | 0 | 1 | 11 | 2 | 8 | 4.89 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 40 | 0 | 2 | 4 | 2.84 | .253 | 0.99 | 6.8 | 2.3 | 12.7 | 44.1 | 33 | 14 | 14 | 6 | 11 | 62 | 0 | 12 | 1 | 0 | 0 | 1 | 0 | 2.77 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 73 | 12 | 0 | 0 | 0 | 5.87 | .313 | 1.37 | 9.0 | 3.6 | 7.8 | 15.1 | 15 | 10 | 10 | 5 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.80 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 11 | 0 | 2 | 1 | 3.13 | .250 | 0.96 | 6.7 | 2.0 | 5.3 | 46.0 | 34 | 16 | 16 | 5 | 10 | 27 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.02 |