| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 25 | 25 | 12 | 11 | 4.22 | .300 | 1.28 | 9.8 | 1.8 | 9.1 | 185.2 | 202 | 94 | 87 | 36 | 36 | 188 | 6 | 0 | 0 | 1 | 12 | 1 | 4 | 4.10 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 24 | 24 | 7 | 13 | 5.39 | .321 | 1.39 | 9.1 | 3.4 | 9.3 | 165.1 | 166 | 100 | 99 | 29 | 63 | 170 | 2 | 0 | 0 | 0 | 10 | 5 | 10 | 4.46 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 24 | 24 | 10 | 9 | 4.41 | .331 | 1.42 | 9.0 | 3.8 | 6.7 | 169.1 | 169 | 88 | 83 | 23 | 72 | 125 | 0 | 0 | 0 | 0 | 10 | 10 | 4 | 4.75 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 24 | 24 | 8 | 10 | 6.00 | .321 | 1.40 | 9.0 | 3.6 | 6.3 | 150.0 | 150 | 105 | 100 | 37 | 60 | 105 | 1 | 0 | 0 | 0 | 11 | 3 | 5 | 6.07 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 23 | 23 | 11 | 10 | 6.09 | .334 | 1.49 | 11.1 | 2.3 | 9.1 | 158.0 | 194 | 108 | 107 | 33 | 41 | 160 | 3 | 0 | 0 | 0 | 9 | 3 | 4 | 4.53 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 71 | 0 | 1 | 0 | 3.89 | .273 | 1.13 | 7.2 | 3.1 | 11.2 | 41.2 | 33 | 18 | 18 | 5 | 14 | 51 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.12 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 69 | 0 | 3 | 3 | 3.60 | .323 | 1.37 | 8.4 | 3.9 | 9.4 | 65.0 | 61 | 33 | 26 | 13 | 28 | 68 | 0 | 5 | 6 | 0 | 0 | 4 | 0 | 4.98 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 59 | 0 | 2 | 5 | 4.42 | .332 | 1.40 | 8.7 | 3.9 | 11.8 | 55.0 | 53 | 29 | 27 | 10 | 24 | 72 | 0 | 12 | 4 | 0 | 0 | 5 | 4 | 4.33 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 40 | 0 | 3 | 2 | 4.38 | .316 | 1.33 | 8.3 | 3.7 | 9.0 | 39.0 | 36 | 20 | 19 | 3 | 16 | 39 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 3.38 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 26 | 0 | 0 | 0 | 5.76 | .342 | 1.52 | 11.2 | 2.5 | 7.9 | 25.0 | 31 | 16 | 16 | 5 | 7 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.80 |