| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 34 | 34 | 18 | 11 | 3.45 | .289 | 1.21 | 7.8 | 3.1 | 6.8 | 237.2 | 205 | 92 | 91 | 35 | 82 | 178 | 3 | 0 | 0 | 1 | 21 | 3 | 7 | 4.49 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 72 | 32 | 32 | 11 | 8 | 5.02 | .317 | 1.37 | 8.9 | 3.4 | 7.3 | 174.0 | 173 | 103 | 97 | 33 | 65 | 141 | 0 | 0 | 0 | 0 | 15 | 4 | 3 | 5.03 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 96 | 91 | 0 | 8 | 3 | 2.77 | .263 | 1.01 | 6.5 | 2.6 | 10.4 | 120.1 | 87 | 37 | 37 | 14 | 35 | 138 | 0 | 13 | 3 | 0 | 0 | 7 | 2 | 3.27 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 88 | 81 | 0 | 8 | 3 | 3.27 | .295 | 1.22 | 6.8 | 4.2 | 9.7 | 99.0 | 75 | 37 | 36 | 15 | 46 | 107 | 0 | 12 | 2 | 0 | 0 | 3 | 0 | 4.29 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 56 | 0 | 2 | 4 | 4.79 | .321 | 1.40 | 8.4 | 4.3 | 8.2 | 71.1 | 66 | 38 | 38 | 11 | 34 | 65 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 4.66 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 43 | 0 | 3 | 1 | 3.04 | .296 | 1.24 | 6.6 | 4.7 | 12.7 | 56.1 | 41 | 19 | 19 | 4 | 29 | 79 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 2.71 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 39 | 0 | 0 | 0 | 3.57 | .320 | 1.35 | 7.4 | 4.8 | 9.2 | 45.1 | 37 | 20 | 18 | 4 | 24 | 46 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 3.91 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 41 | 0 | 4 | 3 | 4.44 | .309 | 1.32 | 7.9 | 4.1 | 9.7 | 50.2 | 44 | 27 | 25 | 13 | 23 | 54 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 5.66 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 50 | 21 | 0 | 2 | 2 | 6.37 | .369 | 1.70 | 10.5 | 4.9 | 5.7 | 35.1 | 41 | 25 | 25 | 3 | 19 | 22 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 4.66 |