| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 34 | 34 | 18 | 11 | 4.17 | .304 | 1.31 | 8.5 | 3.3 | 8.6 | 228.2 | 215 | 108 | 106 | 28 | 84 | 219 | 2 | 0 | 0 | 2 | 22 | 1 | 8 | 3.79 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 32 | 32 | 9 | 14 | 5.61 | .339 | 1.51 | 9.8 | 3.9 | 7.3 | 200.2 | 218 | 126 | 125 | 38 | 86 | 162 | 6 | 0 | 0 | 2 | 11 | 5 | 3 | 5.22 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 32 | 31 | 10 | 16 | 4.48 | .328 | 1.45 | 9.9 | 3.2 | 7.2 | 207.0 | 227 | 111 | 103 | 38 | 73 | 165 | 3 | 0 | 1 | 0 | 15 | 3 | 6 | 4.89 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 80 | 0 | 5 | 6 | 4.73 | .327 | 1.45 | 8.0 | 5.0 | 10.7 | 91.1 | 81 | 48 | 48 | 14 | 51 | 108 | 0 | 1 | 1 | 0 | 0 | 1 | 7 | 4.34 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 79 | 0 | 2 | 5 | 2.70 | .286 | 1.19 | 8.0 | 2.7 | 10.5 | 80.0 | 71 | 24 | 24 | 9 | 24 | 93 | 0 | 41 | 4 | 0 | 0 | 1 | 1 | 3.08 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 49 | 0 | 1 | 3 | 4.91 | .327 | 1.44 | 8.9 | 4.2 | 9.3 | 62.1 | 61 | 35 | 34 | 11 | 29 | 64 | 0 | 1 | 0 | 0 | 0 | 1 | 6 | 4.69 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 41 | 0 | 2 | 2 | 3.71 | .305 | 1.29 | 6.5 | 5.1 | 9.4 | 51.0 | 37 | 21 | 21 | 5 | 29 | 53 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.96 |