| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 25 | 25 | 10 | 12 | 3.25 | .282 | 1.15 | 7.2 | 3.2 | 8.0 | 182.2 | 146 | 70 | 66 | 17 | 64 | 161 | 3 | 0 | 0 | 1 | 15 | 5 | 5 | 3.58 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 24 | 24 | 4 | 11 | 5.26 | .333 | 1.43 | 9.5 | 3.4 | 8.9 | 143.2 | 151 | 89 | 84 | 23 | 54 | 142 | 0 | 0 | 0 | 0 | 11 | 10 | 4 | 4.45 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 25 | 24 | 7 | 8 | 4.75 | .318 | 1.37 | 8.9 | 3.5 | 6.5 | 163.0 | 161 | 91 | 86 | 24 | 63 | 117 | 3 | 0 | 0 | 1 | 11 | 4 | 3 | 4.71 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 63 | 0 | 4 | 4 | 3.91 | .310 | 1.32 | 7.4 | 4.4 | 11.9 | 69.0 | 57 | 31 | 30 | 9 | 34 | 91 | 0 | 1 | 1 | 0 | 0 | 2 | 4 | 3.62 |
| CL | Green, C.Green, Chad † >> | 26 | 2017 | R | 95 | 46 | 0 | 4 | 7 | 3.15 | .300 | 1.25 | 7.7 | 3.7 | 9.7 | 54.1 | 46 | 19 | 19 | 8 | 22 | 58 | 0 | 22 | 4 | 0 | 0 | 2 | 0 | 4.11 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 45 | 0 | 3 | 0 | 3.44 | .262 | 1.07 | 6.6 | 3.1 | 11.6 | 49.2 | 36 | 22 | 19 | 8 | 17 | 63 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.59 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 39 | 0 | 7 | 0 | 3.55 | .312 | 1.34 | 7.2 | 5.0 | 8.8 | 50.2 | 40 | 23 | 20 | 4 | 28 | 49 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.82 |