| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 25 | 25 | 9 | 12 | 4.45 | .327 | 1.42 | 10.0 | 2.8 | 10.8 | 149.2 | 166 | 83 | 74 | 19 | 46 | 179 | 0 | 0 | 0 | 0 | 13 | 6 | 0 | 3.30 |
| SP | Brown, H.Brown, Hunter >> | 26 | 2025 | R | 92 | 24 | 24 | 8 | 9 | 4.52 | .312 | 1.34 | 8.6 | 3.6 | 10.2 | 147.1 | 140 | 78 | 74 | 21 | 58 | 166 | 1 | 0 | 0 | 1 | 11 | 2 | 0 | 3.82 |
| SP | Bubic, K.Bubic, Kris # >> | 27 | 2025 | L | 73 | 24 | 24 | 6 | 13 | 4.89 | .331 | 1.47 | 10.0 | 3.3 | 9.5 | 130.2 | 145 | 78 | 71 | 22 | 47 | 137 | 1 | 0 | 0 | 1 | 7 | 2 | 2 | 4.22 |
| SP | Kirby, G.Kirby, George >> | 27 | 2025 | R | 65 | 25 | 24 | 3 | 10 | 6.41 | .364 | 1.69 | 12.3 | 2.9 | 11.3 | 119.1 | 163 | 89 | 85 | 24 | 39 | 150 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.16 |
| RP | Raley, B.Raley, Brooks >> | 37 | 2025 | L | 97 | 66 | 0 | 5 | 2 | 3.96 | .300 | 1.27 | 7.9 | 3.7 | 9.9 | 88.2 | 77 | 42 | 39 | 11 | 36 | 97 | 0 | 5 | 5 | 0 | 0 | 1 | 0 | 3.68 |
| RP | Cleavinger, G.Cleavinger, Garrett >> | 31 | 2025 | L | 93 | 63 | 0 | 4 | 4 | 2.96 | .303 | 1.24 | 7.1 | 4.1 | 12.1 | 82.0 | 65 | 29 | 27 | 9 | 37 | 110 | 0 | 4 | 1 | 0 | 0 | 5 | 1 | 3.28 |
| RP | Kittredge, A.Kittredge, Andrew >> | 35 | 2025 | R | 82 | 58 | 0 | 2 | 4 | 2.96 | .255 | 1.00 | 7.3 | 1.7 | 11.1 | 76.0 | 62 | 27 | 25 | 13 | 14 | 94 | 0 | 7 | 1 | 0 | 0 | 2 | 2 | 3.38 |
| RP | Finnegan, K.Finnegan, Kyle >> | 33 | 2025 | R | 62 | 38 | 0 | 0 | 6 | 6.69 | .397 | 1.95 | 14.8 | 2.8 | 7.2 | 39.0 | 64 | 37 | 29 | 10 | 12 | 31 | 0 | 6 | 2 | 0 | 0 | 1 | 1 | 5.74 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 57 | 32 | 0 | 1 | 1 | 6.75 | .410 | 2.09 | 13.2 | 6.0 | 11.7 | 30.2 | 44 | 26 | 23 | 5 | 20 | 39 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 4.57 |