| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 30 | 30 | 13 | 10 | 3.10 | .272 | 1.09 | 7.7 | 2.1 | 10.1 | 229.2 | 197 | 86 | 79 | 28 | 53 | 257 | 7 | 0 | 0 | 1 | 22 | 8 | 3 | 3.14 |
| SP | Brown, H.Brown, Hunter >> | 26 | 2025 | R | 92 | 29 | 29 | 11 | 9 | 3.89 | .300 | 1.25 | 8.3 | 3.0 | 9.8 | 206.0 | 189 | 90 | 89 | 29 | 68 | 225 | 1 | 0 | 0 | 0 | 21 | 8 | 0 | 3.75 |
| SP | Gilbert, L.Gilbert, Logan # >> | 28 | 2025 | R | 91 | 28 | 28 | 10 | 10 | 4.90 | .320 | 1.38 | 9.4 | 3.1 | 9.7 | 172.2 | 179 | 97 | 94 | 27 | 59 | 186 | 0 | 0 | 0 | 0 | 16 | 6 | 10 | 4.01 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 81 | 91 | 0 | 3 | 3 | 3.60 | .325 | 1.41 | 8.4 | 4.3 | 8.6 | 85.0 | 79 | 35 | 34 | 9 | 41 | 81 | 0 | 2 | 4 | 0 | 0 | 3 | 2 | 4.02 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 79 | 92 | 0 | 3 | 4 | 2.95 | .279 | 1.12 | 6.8 | 3.3 | 10.5 | 79.1 | 60 | 26 | 26 | 7 | 29 | 92 | 0 | 3 | 1 | 0 | 0 | 3 | 2 | 3.04 |
| RP | Henriquez, R.Henriquez, Ronny # >> | 25 | 2025 | R | 75 | 69 | 0 | 8 | 2 | 4.89 | .313 | 1.35 | 6.8 | 5.4 | 10.4 | 57.0 | 43 | 34 | 31 | 6 | 34 | 66 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.89 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 67 | 64 | 0 | 3 | 2 | 5.80 | .315 | 1.35 | 9.7 | 2.6 | 7.6 | 63.2 | 68 | 41 | 41 | 12 | 18 | 53 | 0 | 0 | 4 | 0 | 0 | 2 | 3 | 4.75 |
| CL | Raley, B.Raley, Brooks † >> | 37 | 2025 | L | 97 | 68 | 0 | 2 | 9 | 1.94 | .260 | 1.03 | 6.3 | 3.0 | 8.9 | 83.1 | 58 | 25 | 18 | 4 | 28 | 82 | 0 | 28 | 5 | 0 | 0 | 2 | 0 | 2.73 |